Inhibition of YAP/TAZ-driven TEAD activity prevents growth of NF2-null schwannoma and meningioma

Schwannoma tumours typically arise on the eighth cranial nerve and are mostly caused by loss of the tumour suppressor Merlin (NF2). There are no approved chemotherapies for these tumours and the surgical removal of the tumour carries a high risk of damage to the eighth or other close cranial nerve t...

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Detalles Bibliográficos
Autores principales: Laraba, Liyam, Hillson, Lily, de Guibert, Julio Grimm, Hewitt, Amy, Jaques, Maisie R, Tang, Tracy T, Post, Leonard, Ercolano, Emanuela, Rai, Ganesha, Yang, Shyh-Ming, Jagger, Daniel J, Woznica, Waldemar, Edwards, Philip, Shivane, Aditya G, Hanemann, C Oliver, Parkinson, David B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115179/
https://www.ncbi.nlm.nih.gov/pubmed/36148553
http://dx.doi.org/10.1093/brain/awac342

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