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High risk oral contraceptive hormones do not directly enhance endothelial cell procoagulant activity in vitro
BACKGROUND: Oral contraceptive (OC) use increases venous thromboembolism risk 2-5-fold. Procoagulant changes can be detected in plasma from OC users even without thrombosis, but cellular mechanisms that provoke thrombosis have not been identified. Endothelial cell (EC) dysfunction is thought to init...
Autores principales: | Bouck, Emma G., Arvanitis, Marios, Osburn, William O., Sang, Yaqiu, Reventun, Paula, Ahmadzia, Homa K., Smith, Nicholas L., Lowenstein, Charles J., Wolberg, Alisa S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115293/ https://www.ncbi.nlm.nih.gov/pubmed/37075041 http://dx.doi.org/10.1371/journal.pone.0284333 |
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