Cargando…
Targeting MCAM for next-generation modulation of leucocyte trafficking
This scientific commentary refers to ‘MCAM(+) brain endothelial cells contribute to neuroinflammation by recruiting pathogenic CD4(+) T lymphocytes’ by Charabati et al. (https://doi.org/10.1093/brain/awac389).
Autores principales: | Schneider-Hohendorf, Tilman, Wiendl, Heinz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115349/ https://www.ncbi.nlm.nih.gov/pubmed/36946303 http://dx.doi.org/10.1093/brain/awad079 |
Ejemplares similares
-
Trafficking of lymphocytes into the CNS
por: Schwab, Nicholas, et al.
Publicado: (2015) -
MCAM/CD146 Signaling via PLCγ1 Leads to Activation of β(1)-Integrins in Memory T-Cells Resulting in Increased Brain Infiltration
por: Zondler, Lisa, et al.
Publicado: (2020) -
Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus
por: Breuer, Johanna, et al.
Publicado: (2018) -
VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of T(H)17 cells
por: Schneider-Hohendorf, Tilman, et al.
Publicado: (2014) -
Ineffective treatment of PML with pembrolizumab: Exhausted memory T-cell subsets as a clue?
por: Pawlitzki, Marc, et al.
Publicado: (2019)