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Subcellular location defines GPCR signal transduction

Intracellular G protein-coupled receptors (GPCRs) can be activated by permeant ligands, which contributes to agonist selectivity. Opioid receptors (ORs) provide a notable example, where opioid drugs rapidly activate ORs in the Golgi apparatus. Our knowledge on intracellular GPCR function remains inc...

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Detalles Bibliográficos
Autores principales:	Radoux-Mergault, Arthur, Oberhauser, Lucie, Aureli, Simone, Gervasio, Francesco Luigi, Stoeber, Miriam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115417/ https://www.ncbi.nlm.nih.gov/pubmed/37075112 http://dx.doi.org/10.1126/sciadv.adf6059

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