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Structural basis for the assembly of the DNA polymerase holoenzyme from a monkeypox virus variant

The ongoing global pandemic caused by a variant of the monkeypox (or mpox) virus (MPXV) has prompted widespread concern. The MPXV DNA polymerase holoenzyme, consisting of F8, A22, and E4, is vital for replicating the viral genome and represents a crucial target for the development of antiviral drugs...

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Detalles Bibliográficos
Autores principales:	Li, Yaning, Shen, Yaping, Hu, Ziwei, Yan, Renhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115419/ https://www.ncbi.nlm.nih.gov/pubmed/37075110 http://dx.doi.org/10.1126/sciadv.adg2331

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