Summary statistics-based association test for identifying the pleiotropic effects with set of genetic variants

MOTIVATION: Traditional genome-wide association study focuses on testing one-to-one relationship between genetic variants and complex human diseases or traits. While its success in the past decade, this one-to-one paradigm lacks efficiency because it does not utilize the information of intrinsic gen...

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Detalles Bibliográficos
Autores principales: Bu, Deliang, Wang, Xiao, Li, Qizhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115469/
https://www.ncbi.nlm.nih.gov/pubmed/37027223
http://dx.doi.org/10.1093/bioinformatics/btad182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115469/
https://www.ncbi.nlm.nih.gov/pubmed/37027223
http://dx.doi.org/10.1093/bioinformatics/btad182

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