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Summary statistics-based association test for identifying the pleiotropic effects with set of genetic variants
MOTIVATION: Traditional genome-wide association study focuses on testing one-to-one relationship between genetic variants and complex human diseases or traits. While its success in the past decade, this one-to-one paradigm lacks efficiency because it does not utilize the information of intrinsic gen...
Autores principales: | Bu, Deliang, Wang, Xiao, Li, Qizhai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115469/ https://www.ncbi.nlm.nih.gov/pubmed/37027223 http://dx.doi.org/10.1093/bioinformatics/btad182 |
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