Postinfantile Giant Cell Hepatitis Secondary to Rheumatoid Arthritis

Postinfantile giant cell hepatitis (PIGCH), also known as syncytial giant cell hepatitis, continues to be a poorly defined and rare disease presentation in the adult population. Although a common finding in neonates, there is limited literature on the disease process, causes, and treatment success o...

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Autores principales: Martinez-Moad, Miranda, Wunderlich, Grant, Diep, Darlene, Vasudevan, Akshay, Russell, Alison, Janitz, Tyler, Aluri, Bineetha, Oviedo, Angelica, Mysore Rangaraju, Ayyappa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115553/
https://www.ncbi.nlm.nih.gov/pubmed/37091202
http://dx.doi.org/10.14309/crj.0000000000001006
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author Martinez-Moad, Miranda
Wunderlich, Grant
Diep, Darlene
Vasudevan, Akshay
Russell, Alison
Janitz, Tyler
Aluri, Bineetha
Oviedo, Angelica
Mysore Rangaraju, Ayyappa
author_facet Martinez-Moad, Miranda
Wunderlich, Grant
Diep, Darlene
Vasudevan, Akshay
Russell, Alison
Janitz, Tyler
Aluri, Bineetha
Oviedo, Angelica
Mysore Rangaraju, Ayyappa
author_sort Martinez-Moad, Miranda
collection PubMed
description Postinfantile giant cell hepatitis (PIGCH), also known as syncytial giant cell hepatitis, continues to be a poorly defined and rare disease presentation in the adult population. Although a common finding in neonates, there is limited literature on the disease process, causes, and treatment success of PIGCH in adults. A strong association between autoimmune disorders and PIGCH, considerably so in the case of autoimmune hepatitis, has been established. However, there have been limited to no reports of PIGCH secondary to rheumatoid arthritis. Our clinical case aims to bring forth a vignette of PIGCH to spotlight this ill-defined disease in the adult population and highlight some of the proposed causes, treatments, and laboratory markers.
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spelling pubmed-101155532023-04-20 Postinfantile Giant Cell Hepatitis Secondary to Rheumatoid Arthritis Martinez-Moad, Miranda Wunderlich, Grant Diep, Darlene Vasudevan, Akshay Russell, Alison Janitz, Tyler Aluri, Bineetha Oviedo, Angelica Mysore Rangaraju, Ayyappa ACG Case Rep J Case Report Postinfantile giant cell hepatitis (PIGCH), also known as syncytial giant cell hepatitis, continues to be a poorly defined and rare disease presentation in the adult population. Although a common finding in neonates, there is limited literature on the disease process, causes, and treatment success of PIGCH in adults. A strong association between autoimmune disorders and PIGCH, considerably so in the case of autoimmune hepatitis, has been established. However, there have been limited to no reports of PIGCH secondary to rheumatoid arthritis. Our clinical case aims to bring forth a vignette of PIGCH to spotlight this ill-defined disease in the adult population and highlight some of the proposed causes, treatments, and laboratory markers. Wolters Kluwer 2023-04-19 /pmc/articles/PMC10115553/ /pubmed/37091202 http://dx.doi.org/10.14309/crj.0000000000001006 Text en © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Martinez-Moad, Miranda
Wunderlich, Grant
Diep, Darlene
Vasudevan, Akshay
Russell, Alison
Janitz, Tyler
Aluri, Bineetha
Oviedo, Angelica
Mysore Rangaraju, Ayyappa
Postinfantile Giant Cell Hepatitis Secondary to Rheumatoid Arthritis
title Postinfantile Giant Cell Hepatitis Secondary to Rheumatoid Arthritis
title_full Postinfantile Giant Cell Hepatitis Secondary to Rheumatoid Arthritis
title_fullStr Postinfantile Giant Cell Hepatitis Secondary to Rheumatoid Arthritis
title_full_unstemmed Postinfantile Giant Cell Hepatitis Secondary to Rheumatoid Arthritis
title_short Postinfantile Giant Cell Hepatitis Secondary to Rheumatoid Arthritis
title_sort postinfantile giant cell hepatitis secondary to rheumatoid arthritis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115553/
https://www.ncbi.nlm.nih.gov/pubmed/37091202
http://dx.doi.org/10.14309/crj.0000000000001006
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