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Management Options for Linear Immunoglobulin A (IgA) Bullous Dermatosis: A Literature Review

Linear immunoglobulin A (IgA) bullous dermatosis (LABD) is an autoimmune condition with various triggers. Because of the lack of randomized controlled trials on LABD treatment, management options are mostly anecdotal. This paper provides a comprehensive review of treatment options from a literature...

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Detalles Bibliográficos
Autores principales: Khan, Madiha, Park, Lily, Skopit, Stanley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115698/
https://www.ncbi.nlm.nih.gov/pubmed/37090290
http://dx.doi.org/10.7759/cureus.36481
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author Khan, Madiha
Park, Lily
Skopit, Stanley
author_facet Khan, Madiha
Park, Lily
Skopit, Stanley
author_sort Khan, Madiha
collection PubMed
description Linear immunoglobulin A (IgA) bullous dermatosis (LABD) is an autoimmune condition with various triggers. Because of the lack of randomized controlled trials on LABD treatment, management options are mostly anecdotal. This paper provides a comprehensive review of treatment options from a literature review of reported treatments to arm clinicians with a guideline for the management of LABD in both pediatric and adult patients as well as those recalcitrant to first-line therapy (dapsone and steroids). We additionally illustrate an algorithm to use for the management of LABD to aid clinicians when faced with unique patient circumstances.
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spelling pubmed-101156982023-04-21 Management Options for Linear Immunoglobulin A (IgA) Bullous Dermatosis: A Literature Review Khan, Madiha Park, Lily Skopit, Stanley Cureus Dermatology Linear immunoglobulin A (IgA) bullous dermatosis (LABD) is an autoimmune condition with various triggers. Because of the lack of randomized controlled trials on LABD treatment, management options are mostly anecdotal. This paper provides a comprehensive review of treatment options from a literature review of reported treatments to arm clinicians with a guideline for the management of LABD in both pediatric and adult patients as well as those recalcitrant to first-line therapy (dapsone and steroids). We additionally illustrate an algorithm to use for the management of LABD to aid clinicians when faced with unique patient circumstances. Cureus 2023-03-21 /pmc/articles/PMC10115698/ /pubmed/37090290 http://dx.doi.org/10.7759/cureus.36481 Text en Copyright © 2023, Khan et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Khan, Madiha
Park, Lily
Skopit, Stanley
Management Options for Linear Immunoglobulin A (IgA) Bullous Dermatosis: A Literature Review
title Management Options for Linear Immunoglobulin A (IgA) Bullous Dermatosis: A Literature Review
title_full Management Options for Linear Immunoglobulin A (IgA) Bullous Dermatosis: A Literature Review
title_fullStr Management Options for Linear Immunoglobulin A (IgA) Bullous Dermatosis: A Literature Review
title_full_unstemmed Management Options for Linear Immunoglobulin A (IgA) Bullous Dermatosis: A Literature Review
title_short Management Options for Linear Immunoglobulin A (IgA) Bullous Dermatosis: A Literature Review
title_sort management options for linear immunoglobulin a (iga) bullous dermatosis: a literature review
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115698/
https://www.ncbi.nlm.nih.gov/pubmed/37090290
http://dx.doi.org/10.7759/cureus.36481
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