Clinical relevance of PD-1 positive CD8 T-cells in gastric cancer

BACKGROUND: We evaluated the relevance of PD-1(+)CD8(+) T-cells in gastric cancer (GC) including prognostic significance, association with chemotherapy and immunotherapy sensitivity and correlations with the tumor microenvironment (TME). METHODS: Discovery cohort: GC samples were evaluated for AE1/3...

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Detalles Bibliográficos
Autores principales: Choo, Joan, Kua, Ley Fang, Soe, Mu Yar, Asuncion, Bernadette Reyna, Tan, Benjamin Kye Jyn, Teo, Chong Boon, Tay, Ryan Yong Kiat, So, Jimmy, Shabbir, Asim, Guowei, Kim, Tan, Hon Lyn, Chan, Gloria, Ma, Haoran, Ramachandran, Gokula Krishnan, Lum, Jeffrey H. Y., Chee, Cheng Ean, Sridharan, Sriram, Tan, Patrick, Sundar, Raghav, Yong, Wei Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115710/
https://www.ncbi.nlm.nih.gov/pubmed/36781556
http://dx.doi.org/10.1007/s10120-023-01364-7

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