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Programmable mammalian translational modulators by CRISPR-associated proteins

Translational modulation based on RNA-binding proteins can be used to construct artificial gene circuits, but RNA-binding proteins capable of regulating translation efficiently and orthogonally remain scarce. Here we report CARTRIDGE (Cas-Responsive Translational Regulation Integratable into Diverse...

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Detalles Bibliográficos
Autores principales: Kawasaki, Shunsuke, Ono, Hiroki, Hirosawa, Moe, Kuwabara, Takeru, Sumi, Shunsuke, Lee, Suji, Woltjen, Knut, Saito, Hirohide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115826/
https://www.ncbi.nlm.nih.gov/pubmed/37076490
http://dx.doi.org/10.1038/s41467-023-37540-7