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Dentin defects caused by a Dspp(−1) frameshift mutation are associated with the activation of autophagy

Dentin sialophosphoprotein (DSPP) is primarily expressed by differentiated odontoblasts (dentin-forming cells), and transiently expressed by presecretory ameloblasts (enamel-forming cells). Disease-causing DSPP mutations predominantly fall into two categories: 5’ mutations affecting targeting and tr...

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Detalles Bibliográficos
Autores principales: Liang, Tian, Smith, Charles E., Hu, Yuanyuan, Zhang, Hong, Zhang, Chuhua, Xu, Qian, Lu, Yongbo, Qi, Ling, Hu, Jan C.-C., Simmer, James P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115861/
https://www.ncbi.nlm.nih.gov/pubmed/37076504
http://dx.doi.org/10.1038/s41598-023-33362-1