Targeting immune checkpoints in anti-neutrophil cytoplasmic antibodies associated vasculitis: the potential therapeutic targets in the future

Anti-neutrophil cytoplasmic autoantibodies (ANCA) associated vasculitis (AAV) is a necrotizing vasculitis mainly involving small blood vessels. It is demonstrated that T cells are important in the pathogenesis of AAV, including regulatory T cells (Treg) and helper T cells (Th), especially Th2, Th17,...

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Detalles Bibliográficos
Autores principales: Pan, Menglu, Zhao, Huanhuan, Jin, Ruimin, Leung, Patrick S. C., Shuai, Zongwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115969/
https://www.ncbi.nlm.nih.gov/pubmed/37090741
http://dx.doi.org/10.3389/fimmu.2023.1156212

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