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A senescence-based prognostic gene signature for colorectal cancer and identification of the role of SPP1-positive macrophages in tumor senescence

BACKGROUND: Senescence is significantly associated with cancer prognosis. This study aimed to construct a senescence-related prognostic model for colorectal cancer (CRC) and to investigate the influence of senescence on the tumor microenvironment. METHODS: Transcriptome and clinical data of CRC case...

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Detalles Bibliográficos
Autores principales:	Yu, Sifei, Chen, Mengdi, Xu, Lili, Mao, Enqiang, Sun, Silei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10115976/ https://www.ncbi.nlm.nih.gov/pubmed/37090726 http://dx.doi.org/10.3389/fimmu.2023.1175490

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