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L-carnitine prevents lenvatinib-induced muscle toxicity without impairment of the anti-angiogenic efficacy
Lenvatinib is an oral tyrosine kinase inhibitor that acts on multiple receptors involved in angiogenesis. Lenvatinib is a standard agent for the treatment of several types of advanced cancers; however, it frequently causes muscle-related adverse reactions. Our previous study revealed that lenvatinib...
Autores principales: | Jing, Zheng, Iba, Tomohiro, Naito, Hisamichi, Xu, Pingping, Morishige, Jun-ichi, Nagata, Naoto, Okubo, Hironao, Ando, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116043/ https://www.ncbi.nlm.nih.gov/pubmed/37089945 http://dx.doi.org/10.3389/fphar.2023.1182788 |
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