Oridonin inhibits inflammation of epithelial cells via dual-targeting of CD31 Keap1 to ameliorate acute lung injury

INTRODCUTION: Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are major causes of COVID-19 mortality. However, drug delivery to lung tissues is impeded by endothelial cell barriers, limiting the efficacy of existing treatments. A prompt and aggressive treatment strategy is the...

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Detalles Bibliográficos
Autores principales: Zhao, Yue, Jin, Hua, Lei, Kawai, Bai, Li-Ping, Pan, Hudan, Wang, Caiyan, Zhu, Xiaoming, Tang, Yanqing, Guo, Zhengyang, Cai, Jiye, Li, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116055/
https://www.ncbi.nlm.nih.gov/pubmed/37090710
http://dx.doi.org/10.3389/fimmu.2023.1163397

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