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Discovery of 3CLpro inhibitor of SARS-CoV-2 main protease

Coronavirus main protease (3CLpro), a special cysteine protease in coronavirus family, is highly desirable in the life cycle of coronavirus. Here, molecular docking, ADMET pharmacokinetic profiles and molecular dynamics (MD) simulation were performed to develop specific 3CLpro inhibitor. The results...

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Detalles Bibliográficos
Autores principales:	Kuang, Yi, Ma, Xiaodong, Shen, Wenjing, Rao, Qingqing, Yang, Shengxiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Future Science Ltd 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116374/ https://www.ncbi.nlm.nih.gov/pubmed/37090493 http://dx.doi.org/10.2144/fsoa-2023-0020

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