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Efficacy of a feed additive consisting of 6‐phytase produced by Komagataella phaffii CGMCC 12056 (APSA PHYTAFEED® 20,000 GR/L) for pigs for fattening (Andrés Pintaluba S.A)
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the efficacy of 6‐phytase produced by the genetically modified strain Komagataella phaffii CGMCC 12056 (APSA PHYTAFEED® 20,000 GR/L) as a zootechnical feed additive (functional group: digestibility en...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116395/ https://www.ncbi.nlm.nih.gov/pubmed/37089176 http://dx.doi.org/10.2903/j.efsa.2023.7973 |
Sumario: | Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the efficacy of 6‐phytase produced by the genetically modified strain Komagataella phaffii CGMCC 12056 (APSA PHYTAFEED® 20,000 GR/L) as a zootechnical feed additive (functional group: digestibility enhancers) for pigs for fattening at a minimum recommended level of 1,000 U /kg feed. In a previous assessment, three trials were submitted; one of them showed significant improvements on zootechnical parameters supporting the efficacy of the additive. The other two trials evaluating apparent faecal phosphorus digestibility and bone mineralisation, showed no improvements on phosphorus retention in bone and, therefore, the FEEDAP Panel could not conclude on the efficacy of the additive. The applicant submitted two new efficacy studies in pigs for fattening evaluating the animal's zootechnical performance, apparent faecal phosphorus digestibility and bone mineralisation. One of the trials was not considered due to high rates of mortality, culling of animals and medical treatments applied. In the other trial, significant improvements on final body weight and apparent total track phosphorus digestibility were found in the animals that received the phytase at 1,000 U/kg complete feed. Owing to the lack of sufficient data, the FEEDAP Panel could not conclude on the efficacy of the additive in pigs for fattening. |
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