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Absorption, metabolism, and excretion of [ (14)C]dersimelagon, an investigational oral selective melanocortin 1 receptor agonist, in preclinical species and healthy volunteers

Dersimelagon (formerly MT‐7117) is a novel, orally administered nonpeptide small molecule selective agonist for melanocortin 1 receptor currently being investigated for the treatment of erythropoietic protoporphyria, X‐linked protoporphyria, and diffuse cutaneous systemic sclerosis (dcSSc). Findings...

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Detalles Bibliográficos
Autores principales:	Tsuda, Minoru, Ogawa, Kei, Endou, Tadashi, Goto, Takahiro, Ogasawara, Yuko, Ogasawara, Akihito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116397/ https://www.ncbi.nlm.nih.gov/pubmed/37078227 http://dx.doi.org/10.1002/prp2.1084

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