Effect of remdesivir post-exposure prophylaxis and treatment on pathogenesis of measles in rhesus macaques

Measles is a systemic disease initiated in the respiratory tract with widespread measles virus (MeV) infection of lymphoid tissue. Mortality can be substantial, but no licensed antiviral therapy is available. We evaluated both post-exposure prophylaxis and treatment with remdesivir, a broad-spectrum...

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Detalles Bibliográficos
Autores principales: Peart Akindele, Nadine A., Katamoni, Laharika Dasharath, Brockhurst, Jacqueline, Ghimire, Shristi, Suwanmanee, San, Pieterse, Lisa, Metcalf Pate, Kelly A., Bunyan, Elaine, Bannister, Roy, Cihlar, Tomas, Porter, Danielle P., Griffin, Diane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116456/
https://www.ncbi.nlm.nih.gov/pubmed/37081035
http://dx.doi.org/10.1038/s41598-023-33572-7

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