Carriers of the p.P522R variant in PLCγ2 have a slightly more responsive immune system

BACKGROUND: The rs72824905 single-nucleotide polymorphism in the PLCG2 gene, encoding the p.P522R residue change in Phospholipase C gamma 2 (PLCγ2), associates with protection against several dementia subtypes and with increased likelihood of longevity. Cell lines and animal models indicated that p....

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Detalles Bibliográficos
Autores principales: Diks, Annieck M., Teodosio, Cristina, de Mooij, Bas, Groenland, Rick J., Naber, Brigitta A. E., de Laat, Inge F., Vloemans, Sandra A., Rohde, Susan, de Jonge, Marien I., Lorenz, Linda, Horsten, Debbie, van Dongen, Jacques J. M., Berkowska, Magdalena A., Holstege, Henne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116473/
https://www.ncbi.nlm.nih.gov/pubmed/37081539
http://dx.doi.org/10.1186/s13024-023-00604-9

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