Laser-Based Mid-Infrared Spectroscopy for Monitoring Temperature-Induced Denaturation of Bovine Serum Albumin and De-/Stabilization Effects of Sugars

[Image: see text] Stability of high-concentration protein formulations is considered a major challenge in current biopharmaceutical development. In this work, we introduce laser-based mid-infrared (IR) spectroscopy as a versatile technique to study the effect of protein concentration and presence of...

Descripción completa

Detalles Bibliográficos
Autores principales: Vijayakumar, Shilpa, Rowlette, Jeremy, Schwaighofer, Andreas, Lendl, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116488/
https://www.ncbi.nlm.nih.gov/pubmed/37010404
http://dx.doi.org/10.1021/acs.analchem.3c00489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116488/
https://www.ncbi.nlm.nih.gov/pubmed/37010404
http://dx.doi.org/10.1021/acs.analchem.3c00489

Ejemplares similares