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Laser-Based Mid-Infrared Spectroscopy for Monitoring Temperature-Induced Denaturation of Bovine Serum Albumin and De-/Stabilization Effects of Sugars

[Image: see text] Stability of high-concentration protein formulations is considered a major challenge in current biopharmaceutical development. In this work, we introduce laser-based mid-infrared (IR) spectroscopy as a versatile technique to study the effect of protein concentration and presence of...

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Detalles Bibliográficos
Autores principales:	Vijayakumar, Shilpa, Rowlette, Jeremy, Schwaighofer, Andreas, Lendl, Bernhard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2023
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116488/ https://www.ncbi.nlm.nih.gov/pubmed/37010404 http://dx.doi.org/10.1021/acs.analchem.3c00489

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