Organotypic human lung bud microarrays identify BMP-dependent SARS-CoV-2 infection in lung cells

Although lung disease is the primary clinical outcome in COVID-19 patients, how SARS-CoV-2 induces lung pathology remains elusive. Here we describe a high-throughput platform to generate self-organizing and commensurate human lung buds derived from hESCs cultured on micropatterned substrates. Lung b...

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Detalles Bibliográficos
Autores principales: Rosado-Olivieri, E.A., Razooky, B., Le Pen, J., De Santis, R., Barrows, D., Sabry, Z., Hoffmann, H.-H., Park, J., Carroll, T.S., Poirier, J.T., Rice, C.M., Brivanlou, A.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116630/
https://www.ncbi.nlm.nih.gov/pubmed/37084725
http://dx.doi.org/10.1016/j.stemcr.2023.03.015

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