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Evidence of kidney injury in preeclampsia: Increased maternal and urinary levels of NGAL and KIM-1 and their enhanced expression in proximal tubule epithelial cells

BACKGROUND AND OBJECTIVE: Proteinuria and glomerular endotheliosis are characteristics of glomerular injury in preeclampsia, a hypertensive disorder in human pregnancy. Neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) are biomarkers of acute/chronic renal tubule...

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Detalles Bibliográficos
Autores principales: Wang, Yuping, Gu, Yang, Gu, Xin, Cooper, Danielle B., Lewis, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116870/
https://www.ncbi.nlm.nih.gov/pubmed/37089603
http://dx.doi.org/10.3389/fmed.2023.1130112