RND Pump-Mediated Efflux of Amotosalen, a Compound Used in Pathogen Inactivation Technology to Enhance Safety of Blood Transfusion Products, May Compromise Its Gram-Negative Anti-Bacterial Activity

Pathogen inactivation is a strategy to improve the safety of transfusion products. The only pathogen reduction technology for blood products currently approved in the US utilizes a psoralen compound, called amotosalen, in combination with UVA light to inactivate bacteria, viruses, and protozoa. Psor...

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Detalles Bibliográficos
Autores principales: Green, Alex B., Chiaraviglio, Lucius, Truelson, Katherine A., Zulauf, Katelyn E., Cui, Meng, Zhang, Zhemin, Ware, Matthew P., Flegel, Willy A., Haspel, Richard L., Yu, Edward W., Kirby, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117049/
https://www.ncbi.nlm.nih.gov/pubmed/36853056
http://dx.doi.org/10.1128/msphere.00673-22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117049/
https://www.ncbi.nlm.nih.gov/pubmed/36853056
http://dx.doi.org/10.1128/msphere.00673-22

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