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An APOBEC3 Mutational Signature in the Genomes of Human-Infecting Orthopoxviruses

The ongoing worldwide monkeypox outbreak is caused by viral lineages (globally referred to as hMPXV1) that are related to but distinct from clade IIb MPXV viruses transmitted within Nigeria. Analysis of the genetic differences has indicated that APOBEC-mediated editing might be responsible for the u...

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Detalles Bibliográficos
Autores principales: Forni, Diego, Cagliani, Rachele, Pozzoli, Uberto, Sironi, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117092/
https://www.ncbi.nlm.nih.gov/pubmed/36920219
http://dx.doi.org/10.1128/msphere.00062-23