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A Genome-Wide Screen in Macrophages Defines Host Genes Regulating the Uptake of Mycobacterium abscessus

The interactions between a host cell and a pathogen can dictate disease outcomes and are important targets for host-directed therapies. Mycobacterium abscessus (Mab) is a highly antibiotic resistant, rapidly growing nontuberculous mycobacterium that infects patients with chronic lung diseases. Mab c...

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Detalles Bibliográficos
Autores principales: Gilliland, Haleigh N., Beckman, Olivia K., Olive, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117111/
https://www.ncbi.nlm.nih.gov/pubmed/36794958
http://dx.doi.org/10.1128/msphere.00663-22