An altered extracellular matrix–integrin interface contributes to Huntington’s disease-associated CNS dysfunction in glial and vascular cells

Astrocytes and brain endothelial cells are components of the neurovascular unit that comprises the blood–brain barrier (BBB) and their dysfunction contributes to pathogenesis in Huntington’s disease (HD). Defining the contribution of these cells to disease can inform cell-type-specific effects and u...

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Detalles Bibliográficos
Autores principales: Hernandez, Sarah J, Lim, Ryan G, Onur, Tarik, Dane, Mark A, Smith, Rebecca, Wang, Keona, Jean, Grace En-Hway, Reyes-Ortiz, Andrea, Devlin, Kaylyn, Miramontes, Ricardo, Wu, Jie, Casale, Malcolm, Kilburn, David, Heiser, Laura M, Korkola, James E, Van Vactor, David, Botas, Juan, Thompson-Peer, Katherine L, Thompson, Leslie M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117161/
https://www.ncbi.nlm.nih.gov/pubmed/36547263
http://dx.doi.org/10.1093/hmg/ddac303

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