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Tibial plateau fractures in older adults are associated with a clinically significant deterioration in health-related quality of life: a propensity score-matched study

AIMS: To investigate health-related quality of life (HRQoL) of older adults (aged ≥ 60 years) after tibial plateau fracture (TPF) compared to preinjury and population matched values, and what aspects of treatment were most important to patients. METHODS: We undertook a retrospective, case-control st...

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Autores principales: Gupta, Shreya, Yapp, Liam Z., Sadczuk, Dominika, MacDonald, Deborah J., Clement, Nick D., White, Tim O., Keating, John F., Scott, Chloe E. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117221/
https://www.ncbi.nlm.nih.gov/pubmed/37078805
http://dx.doi.org/10.1302/2633-1462.44.BJO-2023-0022.R1
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author Gupta, Shreya
Yapp, Liam Z.
Sadczuk, Dominika
MacDonald, Deborah J.
Clement, Nick D.
White, Tim O.
Keating, John F.
Scott, Chloe E. H.
author_facet Gupta, Shreya
Yapp, Liam Z.
Sadczuk, Dominika
MacDonald, Deborah J.
Clement, Nick D.
White, Tim O.
Keating, John F.
Scott, Chloe E. H.
author_sort Gupta, Shreya
collection PubMed
description AIMS: To investigate health-related quality of life (HRQoL) of older adults (aged ≥ 60 years) after tibial plateau fracture (TPF) compared to preinjury and population matched values, and what aspects of treatment were most important to patients. METHODS: We undertook a retrospective, case-control study of 67 patients at mean 3.5 years (SD 1.3; 1.3 to 6.1) after TPF (47 patients underwent fixation, and 20 nonoperative management). Patients completed EuroQol five-dimension three-level (EQ-5D-3L) questionnaire, Lower Limb Function Scale (LEFS), and Oxford Knee Scores (OKS) for current and recalled prefracture status. Propensity score matching for age, sex, and deprivation in a 1:5 ratio was performed using patient level data from the Health Survey for England to obtain a control group for HRQoL comparison. The primary outcome was the difference in actual (TPF cohort) and expected (matched control) EQ-5D-3L score after TPF. RESULTS: TPF patients had a significantly worse EQ-5D-3L utility (mean difference (MD) 0.09, 95% confidence interval (CI) 0.00 to 0.16; p < 0.001) following their injury compared to matched controls, and had a significant deterioration (MD 0.140, 95% CI 0 to 0.309; p < 0.001) relative to their preoperative status. TPF patients had significantly greater pre-fracture EQ-5D-3L scores compared to controls (p = 0.003), specifically in mobility and pain/discomfort domains. A decline in EQ-5D-3L greater than the minimal important change of 0.105 was present in 36/67 TPF patients (53.7%). Following TPF, OKS (MD -7; interquartile range (IQR) -1 to -15) and LEFS (MD -10; IQR -2 to -26) declined significantly (p < 0.001) from pre-fracture levels. Of the 12 elements of fracture care assessed, the most important to patients were getting back to their own home, having a stable knee, and returning to normal function. CONCLUSION: TPFs in older adults were associated with a clinically significant deterioration in HRQoL compared to preinjury level and age, sex, and deprivation matched controls for both undisplaced fractures managed nonoperatively and displaced or unstable fractures managed with internal fixation. Cite this article: Bone Jt Open 2023;4(4):273–282.
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spelling pubmed-101172212023-04-21 Tibial plateau fractures in older adults are associated with a clinically significant deterioration in health-related quality of life: a propensity score-matched study Gupta, Shreya Yapp, Liam Z. Sadczuk, Dominika MacDonald, Deborah J. Clement, Nick D. White, Tim O. Keating, John F. Scott, Chloe E. H. Bone Jt Open Trauma AIMS: To investigate health-related quality of life (HRQoL) of older adults (aged ≥ 60 years) after tibial plateau fracture (TPF) compared to preinjury and population matched values, and what aspects of treatment were most important to patients. METHODS: We undertook a retrospective, case-control study of 67 patients at mean 3.5 years (SD 1.3; 1.3 to 6.1) after TPF (47 patients underwent fixation, and 20 nonoperative management). Patients completed EuroQol five-dimension three-level (EQ-5D-3L) questionnaire, Lower Limb Function Scale (LEFS), and Oxford Knee Scores (OKS) for current and recalled prefracture status. Propensity score matching for age, sex, and deprivation in a 1:5 ratio was performed using patient level data from the Health Survey for England to obtain a control group for HRQoL comparison. The primary outcome was the difference in actual (TPF cohort) and expected (matched control) EQ-5D-3L score after TPF. RESULTS: TPF patients had a significantly worse EQ-5D-3L utility (mean difference (MD) 0.09, 95% confidence interval (CI) 0.00 to 0.16; p < 0.001) following their injury compared to matched controls, and had a significant deterioration (MD 0.140, 95% CI 0 to 0.309; p < 0.001) relative to their preoperative status. TPF patients had significantly greater pre-fracture EQ-5D-3L scores compared to controls (p = 0.003), specifically in mobility and pain/discomfort domains. A decline in EQ-5D-3L greater than the minimal important change of 0.105 was present in 36/67 TPF patients (53.7%). Following TPF, OKS (MD -7; interquartile range (IQR) -1 to -15) and LEFS (MD -10; IQR -2 to -26) declined significantly (p < 0.001) from pre-fracture levels. Of the 12 elements of fracture care assessed, the most important to patients were getting back to their own home, having a stable knee, and returning to normal function. CONCLUSION: TPFs in older adults were associated with a clinically significant deterioration in HRQoL compared to preinjury level and age, sex, and deprivation matched controls for both undisplaced fractures managed nonoperatively and displaced or unstable fractures managed with internal fixation. Cite this article: Bone Jt Open 2023;4(4):273–282. The British Editorial Society of Bone & Joint Surgery 2023-04-20 /pmc/articles/PMC10117221/ /pubmed/37078805 http://dx.doi.org/10.1302/2633-1462.44.BJO-2023-0022.R1 Text en © 2023 Author(s) et al. https://creativecommons.org/licenses/by-nc-nd/4.0/https://online.boneandjoint.org.uk/TDMThis is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc-nd/4.0/
spellingShingle Trauma
Gupta, Shreya
Yapp, Liam Z.
Sadczuk, Dominika
MacDonald, Deborah J.
Clement, Nick D.
White, Tim O.
Keating, John F.
Scott, Chloe E. H.
Tibial plateau fractures in older adults are associated with a clinically significant deterioration in health-related quality of life: a propensity score-matched study
title Tibial plateau fractures in older adults are associated with a clinically significant deterioration in health-related quality of life: a propensity score-matched study
title_full Tibial plateau fractures in older adults are associated with a clinically significant deterioration in health-related quality of life: a propensity score-matched study
title_fullStr Tibial plateau fractures in older adults are associated with a clinically significant deterioration in health-related quality of life: a propensity score-matched study
title_full_unstemmed Tibial plateau fractures in older adults are associated with a clinically significant deterioration in health-related quality of life: a propensity score-matched study
title_short Tibial plateau fractures in older adults are associated with a clinically significant deterioration in health-related quality of life: a propensity score-matched study
title_sort tibial plateau fractures in older adults are associated with a clinically significant deterioration in health-related quality of life: a propensity score-matched study
topic Trauma
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117221/
https://www.ncbi.nlm.nih.gov/pubmed/37078805
http://dx.doi.org/10.1302/2633-1462.44.BJO-2023-0022.R1
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