Systemic LRG1 Expression in Melanoma is Associated with Disease Progression and Recurrence

The response rates upon neoadjuvant immune checkpoint blockade (ICB) in stage III melanoma are higher as compared with stage IV disease. Given that successful ICB depends on systemic immune response, we hypothesized that systemic immune suppression might be a mechanism responsible for lower response...

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Detalles Bibliográficos
Autores principales: Hoefsmit, Esmee P., Völlmy, Franziska, Rozeman, Elisa A., Reijers, Irene L.M., Versluis, Judith M., Hoekman, Liesbeth, van Akkooi, Alexander C.J., Long, Georgina V., Schadendorf, Dirk, Dummer, Reinhard, Altelaar, Maarten, Blank, Christian U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117404/
https://www.ncbi.nlm.nih.gov/pubmed/37089863
http://dx.doi.org/10.1158/2767-9764.CRC-23-0015

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