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Multiple myeloma with unexplained isolated anaemia in a 24year old man- a case report
BACKGROUND: Multiple myeloma (MM) is a disease of the elderly with a median age at presentation of 70 years. It is rare to diagnose MM in individuals less than 40 years and even extremely rare in those less than 30 years of age. MM is usually suspected in those aged 50 years and above having a combi...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Makerere Medical School
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117456/ https://www.ncbi.nlm.nih.gov/pubmed/37092066 http://dx.doi.org/10.4314/ahs.v22i4.9 |
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author | Aworanti, Oladapo Wale Ogundeji, Sunday Peter Adeoye, Olateni Asake Shokunbi, Wuraola Adebola |
author_facet | Aworanti, Oladapo Wale Ogundeji, Sunday Peter Adeoye, Olateni Asake Shokunbi, Wuraola Adebola |
author_sort | Aworanti, Oladapo Wale |
collection | PubMed |
description | BACKGROUND: Multiple myeloma (MM) is a disease of the elderly with a median age at presentation of 70 years. It is rare to diagnose MM in individuals less than 40 years and even extremely rare in those less than 30 years of age. MM is usually suspected in those aged 50 years and above having a combination of hypercalcemia, renal insufficiency, anaemia and bone lesions. Although anaemia is a common clinical feature of MM, it is very rare that anaemia would be the only clinical presentation, hence the need to report this index case. CASE PRESENTATION: We present a rare case of MM in a 24-year- old male who presented with only symptomatic anaemia. Investigations for the cause of anaemia, including Bone marrow aspiration cytology revealed a diagnosis of MM ISS stage II. Here, we highlighted the need to seek early haematologist consultation in investigating patients' whose cause of anaemia is not immediately obvious from the clinical presentation and routine laboratory investigations. CONCLUSION: MM can present at a younger age with unexplained anaemia without bone pains or renal insufficiency. High level of suspicion for MM is required in young patients with unexplained anaemia |
format | Online Article Text |
id | pubmed-10117456 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Makerere Medical School |
record_format | MEDLINE/PubMed |
spelling | pubmed-101174562023-04-21 Multiple myeloma with unexplained isolated anaemia in a 24year old man- a case report Aworanti, Oladapo Wale Ogundeji, Sunday Peter Adeoye, Olateni Asake Shokunbi, Wuraola Adebola Afr Health Sci Articles BACKGROUND: Multiple myeloma (MM) is a disease of the elderly with a median age at presentation of 70 years. It is rare to diagnose MM in individuals less than 40 years and even extremely rare in those less than 30 years of age. MM is usually suspected in those aged 50 years and above having a combination of hypercalcemia, renal insufficiency, anaemia and bone lesions. Although anaemia is a common clinical feature of MM, it is very rare that anaemia would be the only clinical presentation, hence the need to report this index case. CASE PRESENTATION: We present a rare case of MM in a 24-year- old male who presented with only symptomatic anaemia. Investigations for the cause of anaemia, including Bone marrow aspiration cytology revealed a diagnosis of MM ISS stage II. Here, we highlighted the need to seek early haematologist consultation in investigating patients' whose cause of anaemia is not immediately obvious from the clinical presentation and routine laboratory investigations. CONCLUSION: MM can present at a younger age with unexplained anaemia without bone pains or renal insufficiency. High level of suspicion for MM is required in young patients with unexplained anaemia Makerere Medical School 2022-12 /pmc/articles/PMC10117456/ /pubmed/37092066 http://dx.doi.org/10.4314/ahs.v22i4.9 Text en © 2022 Aworanti OW et al. https://creativecommons.org/licenses/by/4.0/Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License (https://creativecommons.org/licenses/BY/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Articles Aworanti, Oladapo Wale Ogundeji, Sunday Peter Adeoye, Olateni Asake Shokunbi, Wuraola Adebola Multiple myeloma with unexplained isolated anaemia in a 24year old man- a case report |
title | Multiple myeloma with unexplained isolated anaemia in a 24year old man- a case report |
title_full | Multiple myeloma with unexplained isolated anaemia in a 24year old man- a case report |
title_fullStr | Multiple myeloma with unexplained isolated anaemia in a 24year old man- a case report |
title_full_unstemmed | Multiple myeloma with unexplained isolated anaemia in a 24year old man- a case report |
title_short | Multiple myeloma with unexplained isolated anaemia in a 24year old man- a case report |
title_sort | multiple myeloma with unexplained isolated anaemia in a 24year old man- a case report |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117456/ https://www.ncbi.nlm.nih.gov/pubmed/37092066 http://dx.doi.org/10.4314/ahs.v22i4.9 |
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