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Opioids, sleep, analgesia and respiratory depression: Their convergence on Mu (μ)-opioid receptors in the parabrachial area

Opioids provide analgesia, as well as modulate sleep and respiration, all by possibly acting on the μ-opioid receptors (MOR). MOR’s are ubiquitously present throughout the brain, posing a challenge for understanding the precise anatomical substrates that mediate opioid induced respiratory depression...

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Detalles Bibliográficos
Autores principales: Lynch, Nicole, Lima, Janayna D., Spinieli, Richard L., Kaur, Satvinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117663/
https://www.ncbi.nlm.nih.gov/pubmed/37090798
http://dx.doi.org/10.3389/fnins.2023.1134842