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Opioids, sleep, analgesia and respiratory depression: Their convergence on Mu (μ)-opioid receptors in the parabrachial area
Opioids provide analgesia, as well as modulate sleep and respiration, all by possibly acting on the μ-opioid receptors (MOR). MOR’s are ubiquitously present throughout the brain, posing a challenge for understanding the precise anatomical substrates that mediate opioid induced respiratory depression...
Autores principales: | Lynch, Nicole, Lima, Janayna D., Spinieli, Richard L., Kaur, Satvinder |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117663/ https://www.ncbi.nlm.nih.gov/pubmed/37090798 http://dx.doi.org/10.3389/fnins.2023.1134842 |
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