H3N2 influenza hemagglutination inhibition method qualification with data driven statistical methods for human clinical trials

INTRODUCTION: Hemagglutination inhibition (HAI) antibody titers to seasonal influenza strains are important surrogates for vaccine-elicited protection. However, HAI assays can be variable across labs, with low sensitivity across diverse viruses due to lack of standardization. Performing qualificatio...

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Detalles Bibliográficos
Autores principales: Sawant, Sheetal, Gurley, Sarah Anne, Overman, R. Glenn, Sharak, Angelina, Mudrak, Sarah V., Oguin, Thomas, Sempowski, Gregory D., Sarzotti-Kelsoe, Marcella, Walter, Emmanuel B., Xie, Hang, Pasetti, Marcela F., Moody, M. Anthony, Tomaras, Georgia D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117676/
https://www.ncbi.nlm.nih.gov/pubmed/37090729
http://dx.doi.org/10.3389/fimmu.2023.1155880

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