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Grad-seq identifies KhpB as a global RNA-binding protein in Clostridioides difficile that regulates toxin production

Much of our current knowledge about cellular RNA–protein complexes in bacteria is derived from analyses in gram-negative model organisms, with the discovery of RNA-binding proteins (RBPs) generally lagging behind in Gram-positive species. Here, we have applied Grad-seq analysis of native RNA–protein...

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Detalles Bibliográficos
Autores principales: Lamm-Schmidt, Vanessa, Fuchs, Manuela, Sulzer, Johannes, Gerovac, Milan, Hör, Jens, Dersch, Petra, Vogel, Jörg, Faber, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117727/
https://www.ncbi.nlm.nih.gov/pubmed/37223250
http://dx.doi.org/10.1093/femsml/uqab004