Contribution of S100A4-expressing fibroblasts to anti-SSA/Ro-associated atrioventricular nodal calcification and soluble S100A4 as a biomarker of clinical severity

BACKGROUND: Fibrosis and dystrophic calcification disrupting conduction tissue architecture are histopathological lesions characterizing cardiac manifestations of neonatal lupus (cardiac-NL) associated with maternal anti-SSA/Ro antibodies. OBJECTIVES: Increased appreciation of heterogeneity in fibro...

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Detalles Bibliográficos
Autores principales: Firl, Christina E. M., Halushka, Marc, Fraser, Nicola, Masson, Mala, Cuneo, Bettina F., Saxena, Amit, Clancy, Robert, Buyon, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117984/
https://www.ncbi.nlm.nih.gov/pubmed/37090702
http://dx.doi.org/10.3389/fimmu.2023.1114808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10117984/
https://www.ncbi.nlm.nih.gov/pubmed/37090702
http://dx.doi.org/10.3389/fimmu.2023.1114808

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