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Study on tinnitus-related electroencephalogram microstates in patients with vestibular schwannomas
Tinnitus is closely associated with cognition functioning. In order to clarify the central reorganization of tinnitus in patients with vestibular schwannoma (VS), this study explored the aberrant dynamics of electroencephalogram (EEG) microstates and their correlations with tinnitus features in VS p...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118047/ https://www.ncbi.nlm.nih.gov/pubmed/37090804 http://dx.doi.org/10.3389/fnins.2023.1159019 |
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author | Zhang, Chi Wang, Xiaoguang Ding, Zhiwei Zhou, Hanwen Liu, Peng Xue, Xinmiao Wang, Li Jiang, Yuke Chen, Jiyue Shen, Weidong Yang, Shiming Wang, Fangyuan |
author_facet | Zhang, Chi Wang, Xiaoguang Ding, Zhiwei Zhou, Hanwen Liu, Peng Xue, Xinmiao Wang, Li Jiang, Yuke Chen, Jiyue Shen, Weidong Yang, Shiming Wang, Fangyuan |
author_sort | Zhang, Chi |
collection | PubMed |
description | Tinnitus is closely associated with cognition functioning. In order to clarify the central reorganization of tinnitus in patients with vestibular schwannoma (VS), this study explored the aberrant dynamics of electroencephalogram (EEG) microstates and their correlations with tinnitus features in VS patients. Clinical and EEG data were collected from 98 VS patients, including 76 with tinnitus and 22 without tinnitus. Microstates were clustered into four categories. Our EEG microstate analysis revealed that VS patients with tinnitus exhibited an increased frequency of microstate C compared to those without tinnitus. Furthermore, correlation analysis demonstrated that the Tinnitus Handicap Inventory (THI) score was negatively associated with the duration of microstate A and positively associated with the frequency of microstate C. These findings suggest that the time series and syntax characteristics of EEG microstates differ significantly between VS patients with and without tinnitus, potentially reflecting abnormal allocation of neural resources and transition of functional brain activity. Our results provide a foundation for developing diverse treatments for tinnitus in VS patients. |
format | Online Article Text |
id | pubmed-10118047 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-101180472023-04-21 Study on tinnitus-related electroencephalogram microstates in patients with vestibular schwannomas Zhang, Chi Wang, Xiaoguang Ding, Zhiwei Zhou, Hanwen Liu, Peng Xue, Xinmiao Wang, Li Jiang, Yuke Chen, Jiyue Shen, Weidong Yang, Shiming Wang, Fangyuan Front Neurosci Neuroscience Tinnitus is closely associated with cognition functioning. In order to clarify the central reorganization of tinnitus in patients with vestibular schwannoma (VS), this study explored the aberrant dynamics of electroencephalogram (EEG) microstates and their correlations with tinnitus features in VS patients. Clinical and EEG data were collected from 98 VS patients, including 76 with tinnitus and 22 without tinnitus. Microstates were clustered into four categories. Our EEG microstate analysis revealed that VS patients with tinnitus exhibited an increased frequency of microstate C compared to those without tinnitus. Furthermore, correlation analysis demonstrated that the Tinnitus Handicap Inventory (THI) score was negatively associated with the duration of microstate A and positively associated with the frequency of microstate C. These findings suggest that the time series and syntax characteristics of EEG microstates differ significantly between VS patients with and without tinnitus, potentially reflecting abnormal allocation of neural resources and transition of functional brain activity. Our results provide a foundation for developing diverse treatments for tinnitus in VS patients. Frontiers Media S.A. 2023-04-06 /pmc/articles/PMC10118047/ /pubmed/37090804 http://dx.doi.org/10.3389/fnins.2023.1159019 Text en Copyright © 2023 Zhang, Wang, Ding, Zhou, Liu, Xue, Wang, Jiang, Chen, Shen, Yang and Wang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neuroscience Zhang, Chi Wang, Xiaoguang Ding, Zhiwei Zhou, Hanwen Liu, Peng Xue, Xinmiao Wang, Li Jiang, Yuke Chen, Jiyue Shen, Weidong Yang, Shiming Wang, Fangyuan Study on tinnitus-related electroencephalogram microstates in patients with vestibular schwannomas |
title | Study on tinnitus-related electroencephalogram microstates in patients with vestibular schwannomas |
title_full | Study on tinnitus-related electroencephalogram microstates in patients with vestibular schwannomas |
title_fullStr | Study on tinnitus-related electroencephalogram microstates in patients with vestibular schwannomas |
title_full_unstemmed | Study on tinnitus-related electroencephalogram microstates in patients with vestibular schwannomas |
title_short | Study on tinnitus-related electroencephalogram microstates in patients with vestibular schwannomas |
title_sort | study on tinnitus-related electroencephalogram microstates in patients with vestibular schwannomas |
topic | Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118047/ https://www.ncbi.nlm.nih.gov/pubmed/37090804 http://dx.doi.org/10.3389/fnins.2023.1159019 |
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