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Characterization of multivalent complexes formed in the presence of more than one conventional antibody to terminal complement component C5

This study sought to understand the nature of the immune complexes that could be formed when a patient is exposed simultaneously to two different anti-complement component 5 (C5) antibodies, such as in patients converting from one bivalent, noncompetitive, C5-binding monoclonal antibody to another....

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Detalles Bibliográficos
Autores principales: Cone, Josh, Kimmel, Lida, Zhang, Yuchun, Johnson, Krista, Sheridan, Douglas, Tamburini, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118082/
https://www.ncbi.nlm.nih.gov/pubmed/37079521
http://dx.doi.org/10.1371/journal.pone.0284502