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The impact of the COVID-19 lockdown on birthweight among singleton term birth in Denmark

In Denmark, a nationwide COVID-19 lockdown was implemented on March 12, 2020 and eased on April 14, 2020. The COVID-19 lockdown featured reduced prevalence of extremely preterm or extremely low birthweight births. This study aims to explore the impact of this COVID-19 lockdown on term birthweights i...

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Autores principales: de Knegt, Victoria E., Hedley, Paula L., Hedermann, Gitte, Wilstrup, Casper, Bækvad-Hansen, Marie, Thagaard, Ida N., Hjalgrim, Henrik, Kanters, Jørgen, Melbye, Mads, Hougaard, David M., Hviid, Anders, Krebs, Lone, Breindahl, Morten, Lausten-Thomsen, Ulrik, Christiansen, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118089/
https://www.ncbi.nlm.nih.gov/pubmed/37079534
http://dx.doi.org/10.1371/journal.pone.0283909
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author de Knegt, Victoria E.
Hedley, Paula L.
Hedermann, Gitte
Wilstrup, Casper
Bækvad-Hansen, Marie
Thagaard, Ida N.
Hjalgrim, Henrik
Kanters, Jørgen
Melbye, Mads
Hougaard, David M.
Hviid, Anders
Krebs, Lone
Breindahl, Morten
Lausten-Thomsen, Ulrik
Christiansen, Michael
author_facet de Knegt, Victoria E.
Hedley, Paula L.
Hedermann, Gitte
Wilstrup, Casper
Bækvad-Hansen, Marie
Thagaard, Ida N.
Hjalgrim, Henrik
Kanters, Jørgen
Melbye, Mads
Hougaard, David M.
Hviid, Anders
Krebs, Lone
Breindahl, Morten
Lausten-Thomsen, Ulrik
Christiansen, Michael
author_sort de Knegt, Victoria E.
collection PubMed
description In Denmark, a nationwide COVID-19 lockdown was implemented on March 12, 2020 and eased on April 14, 2020. The COVID-19 lockdown featured reduced prevalence of extremely preterm or extremely low birthweight births. This study aims to explore the impact of this COVID-19 lockdown on term birthweights in Denmark. We conducted a nationwide register-based cohort study on 27,870 live singleton infants, born at term (weeks 37–41), between March 12 and April 14, 2015–2020, using data from the Danish Neonatal Screening Biobank. Primary outcomes, corrected for confounders, were birthweight, small-for-gestational-age (SGA), and large-for-gestational-age (LGA), comparing the COVID-19 lockdown to the previous five years. Data were analysed using linear regression to assess associations with birthweight. Multinomial logistic regression was used to assess associations with relative-size-for-gestational-age (xGA) categories. Adjusted mean birthweight was significantly increased by 16.9 g (95% CI = 4.1–31.3) during the lockdown period. A dip in mean birthweight was found in gestational weeks 37 and 38 balanced by an increase in weeks 40 and 41. The 2020 lockdown period was associated with an increased LGA prevalence (aOR 1.13, 95% CI = 1.05–1.21). No significant changes in proportions of xGA groups were found between 2015 and 2019. The nationwide COVID-19 lockdown resulted in a small but significant increase in birthweight and proportion of LGA infants, driven by an increase in birthweight in gestational weeks 40 and 41.
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spelling pubmed-101180892023-04-21 The impact of the COVID-19 lockdown on birthweight among singleton term birth in Denmark de Knegt, Victoria E. Hedley, Paula L. Hedermann, Gitte Wilstrup, Casper Bækvad-Hansen, Marie Thagaard, Ida N. Hjalgrim, Henrik Kanters, Jørgen Melbye, Mads Hougaard, David M. Hviid, Anders Krebs, Lone Breindahl, Morten Lausten-Thomsen, Ulrik Christiansen, Michael PLoS One Research Article In Denmark, a nationwide COVID-19 lockdown was implemented on March 12, 2020 and eased on April 14, 2020. The COVID-19 lockdown featured reduced prevalence of extremely preterm or extremely low birthweight births. This study aims to explore the impact of this COVID-19 lockdown on term birthweights in Denmark. We conducted a nationwide register-based cohort study on 27,870 live singleton infants, born at term (weeks 37–41), between March 12 and April 14, 2015–2020, using data from the Danish Neonatal Screening Biobank. Primary outcomes, corrected for confounders, were birthweight, small-for-gestational-age (SGA), and large-for-gestational-age (LGA), comparing the COVID-19 lockdown to the previous five years. Data were analysed using linear regression to assess associations with birthweight. Multinomial logistic regression was used to assess associations with relative-size-for-gestational-age (xGA) categories. Adjusted mean birthweight was significantly increased by 16.9 g (95% CI = 4.1–31.3) during the lockdown period. A dip in mean birthweight was found in gestational weeks 37 and 38 balanced by an increase in weeks 40 and 41. The 2020 lockdown period was associated with an increased LGA prevalence (aOR 1.13, 95% CI = 1.05–1.21). No significant changes in proportions of xGA groups were found between 2015 and 2019. The nationwide COVID-19 lockdown resulted in a small but significant increase in birthweight and proportion of LGA infants, driven by an increase in birthweight in gestational weeks 40 and 41. Public Library of Science 2023-04-20 /pmc/articles/PMC10118089/ /pubmed/37079534 http://dx.doi.org/10.1371/journal.pone.0283909 Text en © 2023 de Knegt et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
de Knegt, Victoria E.
Hedley, Paula L.
Hedermann, Gitte
Wilstrup, Casper
Bækvad-Hansen, Marie
Thagaard, Ida N.
Hjalgrim, Henrik
Kanters, Jørgen
Melbye, Mads
Hougaard, David M.
Hviid, Anders
Krebs, Lone
Breindahl, Morten
Lausten-Thomsen, Ulrik
Christiansen, Michael
The impact of the COVID-19 lockdown on birthweight among singleton term birth in Denmark
title The impact of the COVID-19 lockdown on birthweight among singleton term birth in Denmark
title_full The impact of the COVID-19 lockdown on birthweight among singleton term birth in Denmark
title_fullStr The impact of the COVID-19 lockdown on birthweight among singleton term birth in Denmark
title_full_unstemmed The impact of the COVID-19 lockdown on birthweight among singleton term birth in Denmark
title_short The impact of the COVID-19 lockdown on birthweight among singleton term birth in Denmark
title_sort impact of the covid-19 lockdown on birthweight among singleton term birth in denmark
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118089/
https://www.ncbi.nlm.nih.gov/pubmed/37079534
http://dx.doi.org/10.1371/journal.pone.0283909
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