Cargando…

Pharmacogenomic profile of a central European urban random population-Czech population

The genetic basis of variability in drug response is at the core of pharmacogenomics (PGx) studies, aiming at reducing adverse drug reaction (ADR), which have interethnic variability. This study used the Kardiovize Brno 2030 random urban Czech sample population to analyze polymorphisms in a wide spe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Proietti, Riccardo, Maranho Neto, Geraldo A., Kunzova, Sarka, Lo Re, Oriana, Ahola-Olli, Ari, Heliste, Juho, Gonzalez-Rivas, Juan Pablo, Vinciguerra, Manlio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118108/ https://www.ncbi.nlm.nih.gov/pubmed/37079615 http://dx.doi.org/10.1371/journal.pone.0284386

Ejemplares similares

Determinants of Metabolic Health Across Body Mass Index Categories in Central Europe: A Comparison Between Swiss and Czech Populations
por: Kunzova, Sarka, et al.
Publicado: (2020)

Independent Effects of Hypertension and Obesity on Left Ventricular Mass and Geometry: Evidence from the Cardiovision 2030 Study
por: Maugeri, Andrea, et al.
Publicado: (2019)

Risk Factors Associated with the Consumption of Sugar-Sweetened Beverages among Czech Adults: The Kardiovize Study
por: Kunzova, Monika, et al.
Publicado: (2022)

Histone MacroH2A1: A Chromatin Point of Intersection between Fasting, Senescence and Cellular Regeneration
por: Lo Re, Oriana, et al.
Publicado: (2017)

Dysglycemia and Abnormal Adiposity Drivers of Cardiometabolic-Based Chronic Disease in the Czech Population: Biological, Behavioral, and Cultural/Social Determinants of Health
por: Pavlovska, Iuliia, et al.
Publicado: (2021)

Mono-ADP-Ribosylhydrolase MACROD2 Is Dispensable for Murine Responses to Metabolic and Genotoxic Insults
por: Lo Re, Oriana, et al.
Publicado: (2018)

Macro Histone Variants: Emerging Rheostats of Gastrointestinal Cancers
por: Giallongo, Sebastiano, et al.
Publicado: (2019)

Prevalence of adiposity‐based chronic disease in middle‐aged adults from Czech Republic: The Kardiovize study
por: Gonzalez‐Rivas, Juan P., et al.
Publicado: (2021)

Association of Dietary Patterns with Metabolic Syndrome: Results from the Kardiovize Brno 2030 Study
por: Agodi, Antonella, et al.
Publicado: (2018)

Dog Ownership and Cardiovascular Health: Results From the Kardiovize 2030 Project
por: Maugeri, Andrea, et al.
Publicado: (2019)

Sleep Duration and Excessive Daytime Sleepiness Are Associated with Obesity Independent of Diet and Physical Activity
por: Maugeri, Andrea, et al.
Publicado: (2018)

The Influence of Adiposity Levels on the Relation between Perfluoroalkyl Substances and High Depressive Symptom Scores in Czech Adults
por: Neto, Geraldo, et al.
Publicado: (2023)

Population Pharmacogenomics for Precision Public Health in Colombia
por: Nagar, Shashwat Deepali, et al.
Publicado: (2019)

Is Drinking Alcohol Really Linked to Cardiovascular Health? Evidence from the Kardiovize 2030 Project
por: Maugeri, Andrea, et al.
Publicado: (2020)

Editorial: Pharmacogenomics in neglected populations
por: Botton, Mariana R., et al.
Publicado: (2022)

Population Pharmacogenomics for Health Equity
por: Jordan, I. King, et al.
Publicado: (2023)

Longitudinal Trends in Severe Dyslipidemia in the Czech Population: The Czech MONICA and Czech Post-MONICA Study
por: Cífková, Renata, et al.
Publicado: (2023)

Gut Dysbiosis and Adaptive Immune Response in Diet-induced Obesity vs. Systemic Inflammation
por: Pindjakova, Jana, et al.
Publicado: (2017)

Phosphorylation within Intrinsic Disordered Region Discriminates Histone Variant macroH2A1 Splicing Isoforms—macroH2A1.1 and macroH2A1.2
por: Giallongo, Sebastiano, et al.
Publicado: (2021)

Comparison of COVID-19 epidemic among Czech dentists and the Czech general population
por: Schmidt, Jan, et al.
Publicado: (2023)

The pharmacogenomic landscape of an Indigenous Australian population
por: Samarasinghe, Sumudu Rangika, et al.
Publicado: (2023)

Deficiency of histone variant macroH2A1.1 is associated with sexually dimorphic obesity in mice
por: Chiodi, Valentina, et al.
Publicado: (2023)

Association of Self-Reported Depression Symptoms with Physical Activity Levels in Czechia
por: Maranhao Neto, Geraldo A., et al.
Publicado: (2022)

Population Genetic Difference of Pharmacogenomic VIP Variants in the Tibetan Population
por: He, Chunjuan, et al.
Publicado: (2021)

Editorial: Pharmacogenomics and ethnicity: Prevalence and clinical significance of pharmacogenomic biomarkers in indigenous and other populations
por: Patrinos, George P., et al.
Publicado: (2023)

A Lipidomic Signature Complements Stemness Features Acquisition in Liver Cancer Cells
por: Rivas Serna, Irma Magaly, et al.
Publicado: (2020)

Detection of cell-free histones in the cerebrospinal fluid of pediatric central nervous system malignancies by imaging flow cytometry
por: Buzova, Diana, et al.
Publicado: (2023)

Analysis of Pharmacogenomic Variants Associated with Population Differentiation
por: Yeon, Bora, et al.
Publicado: (2015)

Disease burden and the role of pharmacogenomics in African populations
por: Mpye, K. L., et al.
Publicado: (2017)

Exploring public genomics data for population pharmacogenomics
por: Lakiotaki, Kleanthi, et al.
Publicado: (2017)

Association of Cardiovascular Health with Epicardial Adipose Tissue and Intima Media Thickness: The Kardiovize Study
por: Hruskova, Jana, et al.
Publicado: (2018)

30-year trends in major cardiovascular risk factors in the Czech population, Czech MONICA and Czech post-MONICA, 1985 – 2016/17
por: Cífková, Renata, et al.
Publicado: (2020)

Prediction of Cardiorespiratory Fitness in Czech Adults: Normative Values and Association with Cardiometabolic Health
por: Maranhao Neto, Geraldo A., et al.
Publicado: (2021)

Associations between high triglycerides and arterial stiffness in a population-based sample: Kardiovize Brno 2030 study
por: Pavlovska, Iuliia, et al.
Publicado: (2020)

Frequency of the DPYD * 2A allele in the Czech population
por: Koudová, Monika, et al.
Publicado: (2014)

Evaluation of the Burdening on the Czech Population by Brominated Flame Retardants
por: Logerová, Hana, et al.
Publicado: (2019)

Validation of the Health Consciousness Scale among the Czech Population
por: Remr, Jiri
Publicado: (2023)

Combined genetic and chemical screens indicate protective potential for EGFR inhibition to cardiomyocytes under hypoxia
por: Heliste, Juho, et al.
Publicado: (2021)

A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics
por: Mizzi, Clint, et al.
Publicado: (2016)

Pharmacogenomics of acetaminophen in pediatric populations: a moving target
por: Krasniak, Anne E., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_7gj7r56t2m5jgkqgaj8jdq75q8