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Optimal placebo-treatment comparisons in trials with an incomplete within-subject design and heterogeneous costs and variances
The aim of a clinical trial is to compare placebo to one or more treatments. The within-subject design is known to be more efficient than the between-subject design. However, in some trials that implement a within-subject design it is not possible to evaluate the placebo and all treatments within ea...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118159/ https://www.ncbi.nlm.nih.gov/pubmed/37079588 http://dx.doi.org/10.1371/journal.pone.0283382 |