Zebrafish (Danio rerio) larvae as a predictive model to study gentamicin-induced structural alterations of the kidney

Nephrotoxicity is an important drug safety aspect to be assessed during drug discovery and development. To study renal toxicity, in vitro cell-based assays are often used. Unfortunately, translating the results of such cell assays to vertebrates including human remains challenging. Therefore, we aim...

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Detalles Bibliográficos
Autores principales: Bolten, Jan Stephan, Tanner, Christine, Rodgers, Griffin, Schulz, Georg, Levano, Soledad, Weitkamp, Timm, Waldner, Samuel, Puligilla, Ramya Deepthi, Bodmer, Daniel, Müller, Bert, Huwyler, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118166/
https://www.ncbi.nlm.nih.gov/pubmed/37079551
http://dx.doi.org/10.1371/journal.pone.0284562

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