DSCAM gene triplication causes excessive GABAergic synapses in the neocortex in Down syndrome mouse models

Down syndrome (DS) is caused by the trisomy of human chromosome 21 (HSA21). A major challenge in DS research is to identify the HSA21 genes that cause specific symptoms. Down syndrome cell adhesion molecule (DSCAM) is encoded by a HSA21 gene. Previous studies have shown that the protein level of the...

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Detalles Bibliográficos
Autores principales: Liu, Hao, Caballero-Florán, René N., Hergenreder, Ty, Yang, Tao, Hull, Jacob M., Pan, Geng, Li, Ruonan, Veling, Macy W., Isom, Lori L., Kwan, Kenneth Y., Huang, Z. Josh, Fuerst, Peter G., Jenkins, Paul M., Ye, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118173/
https://www.ncbi.nlm.nih.gov/pubmed/37079499
http://dx.doi.org/10.1371/journal.pbio.3002078

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