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Postoperative Dural Sac Cross-Sectional Area as an Association for Outcome After Surgery for Lumbar Spinal Stenosis: Clinical and Radiological Results From the NORDSTEN-Spinal Stenosis Trial

Prospective cohort study. OBJECTIVE. The aim was to investigate the association between postoperative dural sac cross-sectional area (DSCA) after decompressive surgery for lumbar spinal stenosis and clinical outcome. Furthermore, to investigate if there is a minimum threshold for how extensive a pos...

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Autores principales: Hermansen, Erland, Myklebust, Tor Å., Weber, Clemens, Brisby, Helena, Austevoll, Ivar M., Hellum, Christian, Storheim, Kjersti, Aaen, Jørn, Banitalebi, Hasan, Brox, Jens I., Grundnes, Oliver, Rekeland, Frode, Solberg, Tore, Franssen, Eric, Indrekvam, Kari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118242/
https://www.ncbi.nlm.nih.gov/pubmed/36809364
http://dx.doi.org/10.1097/BRS.0000000000004565
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author Hermansen, Erland
Myklebust, Tor Å.
Weber, Clemens
Brisby, Helena
Austevoll, Ivar M.
Hellum, Christian
Storheim, Kjersti
Aaen, Jørn
Banitalebi, Hasan
Brox, Jens I.
Grundnes, Oliver
Rekeland, Frode
Solberg, Tore
Franssen, Eric
Indrekvam, Kari
author_facet Hermansen, Erland
Myklebust, Tor Å.
Weber, Clemens
Brisby, Helena
Austevoll, Ivar M.
Hellum, Christian
Storheim, Kjersti
Aaen, Jørn
Banitalebi, Hasan
Brox, Jens I.
Grundnes, Oliver
Rekeland, Frode
Solberg, Tore
Franssen, Eric
Indrekvam, Kari
author_sort Hermansen, Erland
collection PubMed
description Prospective cohort study. OBJECTIVE. The aim was to investigate the association between postoperative dural sac cross-sectional area (DSCA) after decompressive surgery for lumbar spinal stenosis and clinical outcome. Furthermore, to investigate if there is a minimum threshold for how extensive a posterior decompression needs to be to achieve a satisfactory clinical result. SUMMARY OF BACKGROUND DATA. There is limited scientific evidence for how extensive lumbar decompression needs to be to obtain a good clinical outcome in patients with symptomatic lumbar spinal stenosis. MATERIALS AND METHODS. All patients were included in the Spinal Stenosis Trial of the NORwegian Degenerative spondylolisthesis and spinal STENosis (NORDSTEN)-study. The patients underwent decompression according to three different methods. DSCA measured on lumbar magnetic resonance imaging at baseline and at three months follow-up, and patient-reported outcome at baseline and at two-year follow-up were registered in a total of 393 patients. Mean age was 68 (SD: 8.3), proportion of males were 204/393 (52%), proportion of smokers were 80/393 (20%), and mean body mass index was 27.8 (SD: 4.2). The cohort was divided into quintiles based on the achieved DSCA postoperatively, the numeric, and relative increase of DSCA, and the association between the increase in DSCA and clinical outcome were evaluated. RESULTS. At baseline, the mean DSCA in the whole cohort was 51.1 mm(2) (SD: 21.1). Postoperatively the area increased to a mean area of 120.6 mm(2) (SD: 46.9). The change in Oswestry disability index in the quintile with the largest DSCA was −22.0 (95% CI: −25.6 to −18), and in the quintile with the lowest DSCA the Oswestry disability index change was −18.9 (95% CI: −22.4 to −15.3). There were only minor differences in clinical improvement for patients in the different DSCA quintiles. CONCLUSION. Less aggressive decompression performed similarly to wider decompression across multiple different patient-reported outcome measures at two years following surgery.
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spelling pubmed-101182422023-04-21 Postoperative Dural Sac Cross-Sectional Area as an Association for Outcome After Surgery for Lumbar Spinal Stenosis: Clinical and Radiological Results From the NORDSTEN-Spinal Stenosis Trial Hermansen, Erland Myklebust, Tor Å. Weber, Clemens Brisby, Helena Austevoll, Ivar M. Hellum, Christian Storheim, Kjersti Aaen, Jørn Banitalebi, Hasan Brox, Jens I. Grundnes, Oliver Rekeland, Frode Solberg, Tore Franssen, Eric Indrekvam, Kari Spine (Phila Pa 1976) Clinical Case Series Prospective cohort study. OBJECTIVE. The aim was to investigate the association between postoperative dural sac cross-sectional area (DSCA) after decompressive surgery for lumbar spinal stenosis and clinical outcome. Furthermore, to investigate if there is a minimum threshold for how extensive a posterior decompression needs to be to achieve a satisfactory clinical result. SUMMARY OF BACKGROUND DATA. There is limited scientific evidence for how extensive lumbar decompression needs to be to obtain a good clinical outcome in patients with symptomatic lumbar spinal stenosis. MATERIALS AND METHODS. All patients were included in the Spinal Stenosis Trial of the NORwegian Degenerative spondylolisthesis and spinal STENosis (NORDSTEN)-study. The patients underwent decompression according to three different methods. DSCA measured on lumbar magnetic resonance imaging at baseline and at three months follow-up, and patient-reported outcome at baseline and at two-year follow-up were registered in a total of 393 patients. Mean age was 68 (SD: 8.3), proportion of males were 204/393 (52%), proportion of smokers were 80/393 (20%), and mean body mass index was 27.8 (SD: 4.2). The cohort was divided into quintiles based on the achieved DSCA postoperatively, the numeric, and relative increase of DSCA, and the association between the increase in DSCA and clinical outcome were evaluated. RESULTS. At baseline, the mean DSCA in the whole cohort was 51.1 mm(2) (SD: 21.1). Postoperatively the area increased to a mean area of 120.6 mm(2) (SD: 46.9). The change in Oswestry disability index in the quintile with the largest DSCA was −22.0 (95% CI: −25.6 to −18), and in the quintile with the lowest DSCA the Oswestry disability index change was −18.9 (95% CI: −22.4 to −15.3). There were only minor differences in clinical improvement for patients in the different DSCA quintiles. CONCLUSION. Less aggressive decompression performed similarly to wider decompression across multiple different patient-reported outcome measures at two years following surgery. Lippincott Williams & Wilkins 2023-05-15 2023-02-20 /pmc/articles/PMC10118242/ /pubmed/36809364 http://dx.doi.org/10.1097/BRS.0000000000004565 Text en © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Clinical Case Series
Hermansen, Erland
Myklebust, Tor Å.
Weber, Clemens
Brisby, Helena
Austevoll, Ivar M.
Hellum, Christian
Storheim, Kjersti
Aaen, Jørn
Banitalebi, Hasan
Brox, Jens I.
Grundnes, Oliver
Rekeland, Frode
Solberg, Tore
Franssen, Eric
Indrekvam, Kari
Postoperative Dural Sac Cross-Sectional Area as an Association for Outcome After Surgery for Lumbar Spinal Stenosis: Clinical and Radiological Results From the NORDSTEN-Spinal Stenosis Trial
title Postoperative Dural Sac Cross-Sectional Area as an Association for Outcome After Surgery for Lumbar Spinal Stenosis: Clinical and Radiological Results From the NORDSTEN-Spinal Stenosis Trial
title_full Postoperative Dural Sac Cross-Sectional Area as an Association for Outcome After Surgery for Lumbar Spinal Stenosis: Clinical and Radiological Results From the NORDSTEN-Spinal Stenosis Trial
title_fullStr Postoperative Dural Sac Cross-Sectional Area as an Association for Outcome After Surgery for Lumbar Spinal Stenosis: Clinical and Radiological Results From the NORDSTEN-Spinal Stenosis Trial
title_full_unstemmed Postoperative Dural Sac Cross-Sectional Area as an Association for Outcome After Surgery for Lumbar Spinal Stenosis: Clinical and Radiological Results From the NORDSTEN-Spinal Stenosis Trial
title_short Postoperative Dural Sac Cross-Sectional Area as an Association for Outcome After Surgery for Lumbar Spinal Stenosis: Clinical and Radiological Results From the NORDSTEN-Spinal Stenosis Trial
title_sort postoperative dural sac cross-sectional area as an association for outcome after surgery for lumbar spinal stenosis: clinical and radiological results from the nordsten-spinal stenosis trial
topic Clinical Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118242/
https://www.ncbi.nlm.nih.gov/pubmed/36809364
http://dx.doi.org/10.1097/BRS.0000000000004565
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