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Not Your Everyday Duodenal Ulcer: Massive Gastrointestinal Bleed Secondary to Extramedullary Plasma Cell Myeloma

The differential for gastrointestinal (GI) bleeding is broad, ranging from peptic ulcers and Helicobacter pylori infection to variceal hemorrhage and neoplasms. The rarer causes of GI bleeds are frequently overlooked and as such can ultimately be more dangerous. Extramedullary multiple myeloma, an a...

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Detalles Bibliográficos
Autores principales: Fiske, Hannah, Dougherty, Brian, Ward, Christopher, Claus, Jessica, Dannheim, Katelyn, Chen, Sonja, Ferreira, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118377/
https://www.ncbi.nlm.nih.gov/pubmed/37091203
http://dx.doi.org/10.14309/crj.0000000000001040
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author Fiske, Hannah
Dougherty, Brian
Ward, Christopher
Claus, Jessica
Dannheim, Katelyn
Chen, Sonja
Ferreira, Jason
author_facet Fiske, Hannah
Dougherty, Brian
Ward, Christopher
Claus, Jessica
Dannheim, Katelyn
Chen, Sonja
Ferreira, Jason
author_sort Fiske, Hannah
collection PubMed
description The differential for gastrointestinal (GI) bleeding is broad, ranging from peptic ulcers and Helicobacter pylori infection to variceal hemorrhage and neoplasms. The rarer causes of GI bleeds are frequently overlooked and as such can ultimately be more dangerous. Extramedullary multiple myeloma, an atypical plasma cell dyscrasia arising outside of the bone marrow, involves the GI tract in <5% of cases and often presents with nonspecific symptoms. We describe a rare case of such GI involvement of a plasma cell tumor, with subsequent transmural duodenal ulceration involving the gastroduodenal artery, ultimately resulting in a fatal GI bleed.
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spelling pubmed-101183772023-04-21 Not Your Everyday Duodenal Ulcer: Massive Gastrointestinal Bleed Secondary to Extramedullary Plasma Cell Myeloma Fiske, Hannah Dougherty, Brian Ward, Christopher Claus, Jessica Dannheim, Katelyn Chen, Sonja Ferreira, Jason ACG Case Rep J Case Report The differential for gastrointestinal (GI) bleeding is broad, ranging from peptic ulcers and Helicobacter pylori infection to variceal hemorrhage and neoplasms. The rarer causes of GI bleeds are frequently overlooked and as such can ultimately be more dangerous. Extramedullary multiple myeloma, an atypical plasma cell dyscrasia arising outside of the bone marrow, involves the GI tract in <5% of cases and often presents with nonspecific symptoms. We describe a rare case of such GI involvement of a plasma cell tumor, with subsequent transmural duodenal ulceration involving the gastroduodenal artery, ultimately resulting in a fatal GI bleed. Wolters Kluwer 2023-04-20 /pmc/articles/PMC10118377/ /pubmed/37091203 http://dx.doi.org/10.14309/crj.0000000000001040 Text en © 2023 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of The American College of Gastroenterology. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Case Report
Fiske, Hannah
Dougherty, Brian
Ward, Christopher
Claus, Jessica
Dannheim, Katelyn
Chen, Sonja
Ferreira, Jason
Not Your Everyday Duodenal Ulcer: Massive Gastrointestinal Bleed Secondary to Extramedullary Plasma Cell Myeloma
title Not Your Everyday Duodenal Ulcer: Massive Gastrointestinal Bleed Secondary to Extramedullary Plasma Cell Myeloma
title_full Not Your Everyday Duodenal Ulcer: Massive Gastrointestinal Bleed Secondary to Extramedullary Plasma Cell Myeloma
title_fullStr Not Your Everyday Duodenal Ulcer: Massive Gastrointestinal Bleed Secondary to Extramedullary Plasma Cell Myeloma
title_full_unstemmed Not Your Everyday Duodenal Ulcer: Massive Gastrointestinal Bleed Secondary to Extramedullary Plasma Cell Myeloma
title_short Not Your Everyday Duodenal Ulcer: Massive Gastrointestinal Bleed Secondary to Extramedullary Plasma Cell Myeloma
title_sort not your everyday duodenal ulcer: massive gastrointestinal bleed secondary to extramedullary plasma cell myeloma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118377/
https://www.ncbi.nlm.nih.gov/pubmed/37091203
http://dx.doi.org/10.14309/crj.0000000000001040
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