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Lipid disorders among Black Africans non-users of lipid-lowering medication

OBJECTIVE: Angola is a sub-Saharan African country where the population has scarce access to lipidlowering medication. We sought to determine the frequency of lipid disorders among Angolan nonusers of lipid-lowering medication. MATERIAL AND METHODS: A cross-sectional descriptive study was carried ou...

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Detalles Bibliográficos
Autores principales: Borgo, Mariana Veronez, Baldo, Marcelo Perim, Alvim, Rafael de Oliveira, Zaniqueli, Divanei, Capingana, Daniel Pires, Magalhães, Pedro, da Silva, Amilcar Bernardo, Oliosa, Polyana Romano, Sartório, Carmem Luiza, Mill, José Geraldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Endocrinologia e Metabologia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118650/
https://www.ncbi.nlm.nih.gov/pubmed/30462809
http://dx.doi.org/10.20945/2359-3997000000076
Descripción
Sumario:OBJECTIVE: Angola is a sub-Saharan African country where the population has scarce access to lipidlowering medication. We sought to determine the frequency of lipid disorders among Angolan nonusers of lipid-lowering medication. MATERIAL AND METHODS: A cross-sectional descriptive study was carried out in a sample of 604 workers from the public sector. Blood pressure and anthropometric data were measured along with biochemical parameters including total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). LDL-C to HDL-C ratio (LDL-C/HDL-C) was obtained from LDL-C and HDL-C levels. RESULTS: High frequencies of elevated blood pressure (44.8%), metabolic syndrome (20.2%), increased TC (39.2%) and increased LDL-C (19.3%) were found. Low HDL-C was more frequent in women (62.4% vs. 36.1%, p < 0.001). Isolated hypercholesterolemia was more frequent in men (9.6% vs. 2.5%, p < 0.001). Among men TC, TG, LDL-C and LDL-C/HDL-C ratio were higher and HDL-C was lower in obese than in low-weight and normal-weight participants. Among women TC, TG, LDL-C and LDL-C/HDL-C ratio were higher in obese than in normal-weight participants. Significant linear trend of increasing TC and LDL-C levels as age increased was detected for both genders (p for trend < 0.05). CONCLUSION: The results of our study showed a high frequency of lipid disorders in Angolan non-users of lipid-lowering medication.