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Lipid disorders among Black Africans non-users of lipid-lowering medication

OBJECTIVE: Angola is a sub-Saharan African country where the population has scarce access to lipidlowering medication. We sought to determine the frequency of lipid disorders among Angolan nonusers of lipid-lowering medication. MATERIAL AND METHODS: A cross-sectional descriptive study was carried ou...

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Autores principales: Borgo, Mariana Veronez, Baldo, Marcelo Perim, Alvim, Rafael de Oliveira, Zaniqueli, Divanei, Capingana, Daniel Pires, Magalhães, Pedro, da Silva, Amilcar Bernardo, Oliosa, Polyana Romano, Sartório, Carmem Luiza, Mill, José Geraldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Endocrinologia e Metabologia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118650/
https://www.ncbi.nlm.nih.gov/pubmed/30462809
http://dx.doi.org/10.20945/2359-3997000000076
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author Borgo, Mariana Veronez
Baldo, Marcelo Perim
Alvim, Rafael de Oliveira
Zaniqueli, Divanei
Capingana, Daniel Pires
Magalhães, Pedro
da Silva, Amilcar Bernardo
Oliosa, Polyana Romano
Sartório, Carmem Luiza
Mill, José Geraldo
author_facet Borgo, Mariana Veronez
Baldo, Marcelo Perim
Alvim, Rafael de Oliveira
Zaniqueli, Divanei
Capingana, Daniel Pires
Magalhães, Pedro
da Silva, Amilcar Bernardo
Oliosa, Polyana Romano
Sartório, Carmem Luiza
Mill, José Geraldo
author_sort Borgo, Mariana Veronez
collection PubMed
description OBJECTIVE: Angola is a sub-Saharan African country where the population has scarce access to lipidlowering medication. We sought to determine the frequency of lipid disorders among Angolan nonusers of lipid-lowering medication. MATERIAL AND METHODS: A cross-sectional descriptive study was carried out in a sample of 604 workers from the public sector. Blood pressure and anthropometric data were measured along with biochemical parameters including total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). LDL-C to HDL-C ratio (LDL-C/HDL-C) was obtained from LDL-C and HDL-C levels. RESULTS: High frequencies of elevated blood pressure (44.8%), metabolic syndrome (20.2%), increased TC (39.2%) and increased LDL-C (19.3%) were found. Low HDL-C was more frequent in women (62.4% vs. 36.1%, p < 0.001). Isolated hypercholesterolemia was more frequent in men (9.6% vs. 2.5%, p < 0.001). Among men TC, TG, LDL-C and LDL-C/HDL-C ratio were higher and HDL-C was lower in obese than in low-weight and normal-weight participants. Among women TC, TG, LDL-C and LDL-C/HDL-C ratio were higher in obese than in normal-weight participants. Significant linear trend of increasing TC and LDL-C levels as age increased was detected for both genders (p for trend < 0.05). CONCLUSION: The results of our study showed a high frequency of lipid disorders in Angolan non-users of lipid-lowering medication.
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spelling pubmed-101186502023-04-21 Lipid disorders among Black Africans non-users of lipid-lowering medication Borgo, Mariana Veronez Baldo, Marcelo Perim Alvim, Rafael de Oliveira Zaniqueli, Divanei Capingana, Daniel Pires Magalhães, Pedro da Silva, Amilcar Bernardo Oliosa, Polyana Romano Sartório, Carmem Luiza Mill, José Geraldo Arch Endocrinol Metab Original Article OBJECTIVE: Angola is a sub-Saharan African country where the population has scarce access to lipidlowering medication. We sought to determine the frequency of lipid disorders among Angolan nonusers of lipid-lowering medication. MATERIAL AND METHODS: A cross-sectional descriptive study was carried out in a sample of 604 workers from the public sector. Blood pressure and anthropometric data were measured along with biochemical parameters including total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). LDL-C to HDL-C ratio (LDL-C/HDL-C) was obtained from LDL-C and HDL-C levels. RESULTS: High frequencies of elevated blood pressure (44.8%), metabolic syndrome (20.2%), increased TC (39.2%) and increased LDL-C (19.3%) were found. Low HDL-C was more frequent in women (62.4% vs. 36.1%, p < 0.001). Isolated hypercholesterolemia was more frequent in men (9.6% vs. 2.5%, p < 0.001). Among men TC, TG, LDL-C and LDL-C/HDL-C ratio were higher and HDL-C was lower in obese than in low-weight and normal-weight participants. Among women TC, TG, LDL-C and LDL-C/HDL-C ratio were higher in obese than in normal-weight participants. Significant linear trend of increasing TC and LDL-C levels as age increased was detected for both genders (p for trend < 0.05). CONCLUSION: The results of our study showed a high frequency of lipid disorders in Angolan non-users of lipid-lowering medication. Sociedade Brasileira de Endocrinologia e Metabologia 2018-10-01 /pmc/articles/PMC10118650/ /pubmed/30462809 http://dx.doi.org/10.20945/2359-3997000000076 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Borgo, Mariana Veronez
Baldo, Marcelo Perim
Alvim, Rafael de Oliveira
Zaniqueli, Divanei
Capingana, Daniel Pires
Magalhães, Pedro
da Silva, Amilcar Bernardo
Oliosa, Polyana Romano
Sartório, Carmem Luiza
Mill, José Geraldo
Lipid disorders among Black Africans non-users of lipid-lowering medication
title Lipid disorders among Black Africans non-users of lipid-lowering medication
title_full Lipid disorders among Black Africans non-users of lipid-lowering medication
title_fullStr Lipid disorders among Black Africans non-users of lipid-lowering medication
title_full_unstemmed Lipid disorders among Black Africans non-users of lipid-lowering medication
title_short Lipid disorders among Black Africans non-users of lipid-lowering medication
title_sort lipid disorders among black africans non-users of lipid-lowering medication
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118650/
https://www.ncbi.nlm.nih.gov/pubmed/30462809
http://dx.doi.org/10.20945/2359-3997000000076
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