Cargando…
Lipid disorders among Black Africans non-users of lipid-lowering medication
OBJECTIVE: Angola is a sub-Saharan African country where the population has scarce access to lipidlowering medication. We sought to determine the frequency of lipid disorders among Angolan nonusers of lipid-lowering medication. MATERIAL AND METHODS: A cross-sectional descriptive study was carried ou...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Endocrinologia e Metabologia
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118650/ https://www.ncbi.nlm.nih.gov/pubmed/30462809 http://dx.doi.org/10.20945/2359-3997000000076 |
_version_ | 1785028847677210624 |
---|---|
author | Borgo, Mariana Veronez Baldo, Marcelo Perim Alvim, Rafael de Oliveira Zaniqueli, Divanei Capingana, Daniel Pires Magalhães, Pedro da Silva, Amilcar Bernardo Oliosa, Polyana Romano Sartório, Carmem Luiza Mill, José Geraldo |
author_facet | Borgo, Mariana Veronez Baldo, Marcelo Perim Alvim, Rafael de Oliveira Zaniqueli, Divanei Capingana, Daniel Pires Magalhães, Pedro da Silva, Amilcar Bernardo Oliosa, Polyana Romano Sartório, Carmem Luiza Mill, José Geraldo |
author_sort | Borgo, Mariana Veronez |
collection | PubMed |
description | OBJECTIVE: Angola is a sub-Saharan African country where the population has scarce access to lipidlowering medication. We sought to determine the frequency of lipid disorders among Angolan nonusers of lipid-lowering medication. MATERIAL AND METHODS: A cross-sectional descriptive study was carried out in a sample of 604 workers from the public sector. Blood pressure and anthropometric data were measured along with biochemical parameters including total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). LDL-C to HDL-C ratio (LDL-C/HDL-C) was obtained from LDL-C and HDL-C levels. RESULTS: High frequencies of elevated blood pressure (44.8%), metabolic syndrome (20.2%), increased TC (39.2%) and increased LDL-C (19.3%) were found. Low HDL-C was more frequent in women (62.4% vs. 36.1%, p < 0.001). Isolated hypercholesterolemia was more frequent in men (9.6% vs. 2.5%, p < 0.001). Among men TC, TG, LDL-C and LDL-C/HDL-C ratio were higher and HDL-C was lower in obese than in low-weight and normal-weight participants. Among women TC, TG, LDL-C and LDL-C/HDL-C ratio were higher in obese than in normal-weight participants. Significant linear trend of increasing TC and LDL-C levels as age increased was detected for both genders (p for trend < 0.05). CONCLUSION: The results of our study showed a high frequency of lipid disorders in Angolan non-users of lipid-lowering medication. |
format | Online Article Text |
id | pubmed-10118650 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Sociedade Brasileira de Endocrinologia e Metabologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-101186502023-04-21 Lipid disorders among Black Africans non-users of lipid-lowering medication Borgo, Mariana Veronez Baldo, Marcelo Perim Alvim, Rafael de Oliveira Zaniqueli, Divanei Capingana, Daniel Pires Magalhães, Pedro da Silva, Amilcar Bernardo Oliosa, Polyana Romano Sartório, Carmem Luiza Mill, José Geraldo Arch Endocrinol Metab Original Article OBJECTIVE: Angola is a sub-Saharan African country where the population has scarce access to lipidlowering medication. We sought to determine the frequency of lipid disorders among Angolan nonusers of lipid-lowering medication. MATERIAL AND METHODS: A cross-sectional descriptive study was carried out in a sample of 604 workers from the public sector. Blood pressure and anthropometric data were measured along with biochemical parameters including total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C) and high-density lipoprotein cholesterol (HDL-C). LDL-C to HDL-C ratio (LDL-C/HDL-C) was obtained from LDL-C and HDL-C levels. RESULTS: High frequencies of elevated blood pressure (44.8%), metabolic syndrome (20.2%), increased TC (39.2%) and increased LDL-C (19.3%) were found. Low HDL-C was more frequent in women (62.4% vs. 36.1%, p < 0.001). Isolated hypercholesterolemia was more frequent in men (9.6% vs. 2.5%, p < 0.001). Among men TC, TG, LDL-C and LDL-C/HDL-C ratio were higher and HDL-C was lower in obese than in low-weight and normal-weight participants. Among women TC, TG, LDL-C and LDL-C/HDL-C ratio were higher in obese than in normal-weight participants. Significant linear trend of increasing TC and LDL-C levels as age increased was detected for both genders (p for trend < 0.05). CONCLUSION: The results of our study showed a high frequency of lipid disorders in Angolan non-users of lipid-lowering medication. Sociedade Brasileira de Endocrinologia e Metabologia 2018-10-01 /pmc/articles/PMC10118650/ /pubmed/30462809 http://dx.doi.org/10.20945/2359-3997000000076 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Borgo, Mariana Veronez Baldo, Marcelo Perim Alvim, Rafael de Oliveira Zaniqueli, Divanei Capingana, Daniel Pires Magalhães, Pedro da Silva, Amilcar Bernardo Oliosa, Polyana Romano Sartório, Carmem Luiza Mill, José Geraldo Lipid disorders among Black Africans non-users of lipid-lowering medication |
title | Lipid disorders among Black Africans non-users of lipid-lowering medication |
title_full | Lipid disorders among Black Africans non-users of lipid-lowering medication |
title_fullStr | Lipid disorders among Black Africans non-users of lipid-lowering medication |
title_full_unstemmed | Lipid disorders among Black Africans non-users of lipid-lowering medication |
title_short | Lipid disorders among Black Africans non-users of lipid-lowering medication |
title_sort | lipid disorders among black africans non-users of lipid-lowering medication |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118650/ https://www.ncbi.nlm.nih.gov/pubmed/30462809 http://dx.doi.org/10.20945/2359-3997000000076 |
work_keys_str_mv | AT borgomarianaveronez lipiddisordersamongblackafricansnonusersoflipidloweringmedication AT baldomarceloperim lipiddisordersamongblackafricansnonusersoflipidloweringmedication AT alvimrafaeldeoliveira lipiddisordersamongblackafricansnonusersoflipidloweringmedication AT zaniquelidivanei lipiddisordersamongblackafricansnonusersoflipidloweringmedication AT capinganadanielpires lipiddisordersamongblackafricansnonusersoflipidloweringmedication AT magalhaespedro lipiddisordersamongblackafricansnonusersoflipidloweringmedication AT dasilvaamilcarbernardo lipiddisordersamongblackafricansnonusersoflipidloweringmedication AT oliosapolyanaromano lipiddisordersamongblackafricansnonusersoflipidloweringmedication AT sartoriocarmemluiza lipiddisordersamongblackafricansnonusersoflipidloweringmedication AT milljosegeraldo lipiddisordersamongblackafricansnonusersoflipidloweringmedication |