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A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism
Clinically nonfunctioning pituitary adenomas (NFPA) are the most common pituitary tumors after prolactinomas. The absence of clinical symptoms of hormonal hypersecretion can contribute to the late diagnosis of the disease. Thus, the majority of patients seek medical attention for signs and symptoms...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Sociedade Brasileira de Endocrinologia e Metabologia
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118716/ https://www.ncbi.nlm.nih.gov/pubmed/27533614 http://dx.doi.org/10.1590/2359-3997000000179 |
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author | Vieira, Leonardo Boguszewski, Cesar L. de Araújo, Luiz Antônio Bronstein, Marcello D. Miranda, Paulo Augusto C. Musolino, Nina R. de C. Naves, Luciana A. Vilar, Lucio Ribeiro-Oliveira, Antônio Gadelha, Mônica R. |
author_facet | Vieira, Leonardo Boguszewski, Cesar L. de Araújo, Luiz Antônio Bronstein, Marcello D. Miranda, Paulo Augusto C. Musolino, Nina R. de C. Naves, Luciana A. Vilar, Lucio Ribeiro-Oliveira, Antônio Gadelha, Mônica R. |
author_sort | Vieira, Leonardo |
collection | PubMed |
description | Clinically nonfunctioning pituitary adenomas (NFPA) are the most common pituitary tumors after prolactinomas. The absence of clinical symptoms of hormonal hypersecretion can contribute to the late diagnosis of the disease. Thus, the majority of patients seek medical attention for signs and symptoms resulting from mass effect, such as neuro-ophthalmologic symptoms and hypopituitarism. Other presentations include pituitary apoplexy or an incidental finding on imaging studies. Mass effect and hypopituitarism impose high morbidity and mortality. However, early diagnosis and effective treatment minimizes morbidity and mortality. In this publication, the goal of the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism is to provide a review of the diagnosis and treatment of patients with NFPA, emphasizing that the treatment should be performed in reference centers. This review is based on data published in the literature and the authors’ experience. Arch Endocrinol Metab. 2016;60(4):374-90 |
format | Online Article Text |
id | pubmed-10118716 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Sociedade Brasileira de Endocrinologia e Metabologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-101187162023-04-21 A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism Vieira, Leonardo Boguszewski, Cesar L. de Araújo, Luiz Antônio Bronstein, Marcello D. Miranda, Paulo Augusto C. Musolino, Nina R. de C. Naves, Luciana A. Vilar, Lucio Ribeiro-Oliveira, Antônio Gadelha, Mônica R. Arch Endocrinol Metab Consensus Clinically nonfunctioning pituitary adenomas (NFPA) are the most common pituitary tumors after prolactinomas. The absence of clinical symptoms of hormonal hypersecretion can contribute to the late diagnosis of the disease. Thus, the majority of patients seek medical attention for signs and symptoms resulting from mass effect, such as neuro-ophthalmologic symptoms and hypopituitarism. Other presentations include pituitary apoplexy or an incidental finding on imaging studies. Mass effect and hypopituitarism impose high morbidity and mortality. However, early diagnosis and effective treatment minimizes morbidity and mortality. In this publication, the goal of the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism is to provide a review of the diagnosis and treatment of patients with NFPA, emphasizing that the treatment should be performed in reference centers. This review is based on data published in the literature and the authors’ experience. Arch Endocrinol Metab. 2016;60(4):374-90 Sociedade Brasileira de Endocrinologia e Metabologia 2016-08-01 /pmc/articles/PMC10118716/ /pubmed/27533614 http://dx.doi.org/10.1590/2359-3997000000179 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Consensus Vieira, Leonardo Boguszewski, Cesar L. de Araújo, Luiz Antônio Bronstein, Marcello D. Miranda, Paulo Augusto C. Musolino, Nina R. de C. Naves, Luciana A. Vilar, Lucio Ribeiro-Oliveira, Antônio Gadelha, Mônica R. A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism |
title | A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism |
title_full | A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism |
title_fullStr | A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism |
title_full_unstemmed | A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism |
title_short | A review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism |
title_sort | review on the diagnosis and treatment of patients with clinically nonfunctioning pituitary adenoma by the neuroendocrinology department of the brazilian society of endocrinology and metabolism |
topic | Consensus |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118716/ https://www.ncbi.nlm.nih.gov/pubmed/27533614 http://dx.doi.org/10.1590/2359-3997000000179 |
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