Cargando…
Probiotic therapy outcomes in body composition of children and adolescent with obesity, a nonrandomized controlled trial
OBJECTIVE: The objective of this study was to evaluate the impact of probiotic supplementation therapy on anthropometric values and body composition of children and adolescent with obesity. SUBJECTS AND METHODS: This is a nonrandomized controlled, prospective, double-blind interventional clinical tr...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Endocrinologia e Metabologia
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118763/ https://www.ncbi.nlm.nih.gov/pubmed/36219201 http://dx.doi.org/10.20945/2359-3997000000526 |
_version_ | 1785028869595594752 |
---|---|
author | Marcelo, Thaís Léo Pacheco Pellicciari, Caroline Rosa Artioli, Thiago Olivetti Leiderman, Dânae Braga Diamante Gradinar, Ana Lúcia Torloni Mimica, Marcelo Kochi, Cristiane |
author_facet | Marcelo, Thaís Léo Pacheco Pellicciari, Caroline Rosa Artioli, Thiago Olivetti Leiderman, Dânae Braga Diamante Gradinar, Ana Lúcia Torloni Mimica, Marcelo Kochi, Cristiane |
author_sort | Marcelo, Thaís Léo Pacheco |
collection | PubMed |
description | OBJECTIVE: The objective of this study was to evaluate the impact of probiotic supplementation therapy on anthropometric values and body composition of children and adolescent with obesity. SUBJECTS AND METHODS: This is a nonrandomized controlled, prospective, double-blind interventional clinical trial with primary data analysis. The sample comprised 44 pubertal children and adolescent (8-17 years old) with obesity. The patients were allocated to probiotic (Lactobacillus rhamnosus) or placebo group, with matching of gender and chronological age. Both groups received nutritional guidance, and were followed for six months. In all patients the anthropometric assessment was carried out by a nutritionist and data on weight, height and waist circumference (WC) were collected. Body composition was assessed using dual emission X-ray absorptiometry (DXA). RESULTS: After six months, both groups had increased weight, height but reduced body index mass (BMI) standard deviation score, with no differences between groups. After the intervention, both groups showed a reduction in the percentage of total body fat and an increase in lean mass, but only the placebo group showed a reduction in the percentage of trunk fat. However, the variation in these parameters did not differ between groups. CONCLUSIONS: The probiotic group does not seem to have benefited from supplementation. However, we suggest that this reduction in BMI SDS in both groups may have occurred due to improvements in diet because of the nutritional advice given throughout the therapy. We concluded that supplementation with this strain of probiotic was not effective in promoting weight loss or improving the body composition of this population. |
format | Online Article Text |
id | pubmed-10118763 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Sociedade Brasileira de Endocrinologia e Metabologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-101187632023-04-21 Probiotic therapy outcomes in body composition of children and adolescent with obesity, a nonrandomized controlled trial Marcelo, Thaís Léo Pacheco Pellicciari, Caroline Rosa Artioli, Thiago Olivetti Leiderman, Dânae Braga Diamante Gradinar, Ana Lúcia Torloni Mimica, Marcelo Kochi, Cristiane Arch Endocrinol Metab Original Article OBJECTIVE: The objective of this study was to evaluate the impact of probiotic supplementation therapy on anthropometric values and body composition of children and adolescent with obesity. SUBJECTS AND METHODS: This is a nonrandomized controlled, prospective, double-blind interventional clinical trial with primary data analysis. The sample comprised 44 pubertal children and adolescent (8-17 years old) with obesity. The patients were allocated to probiotic (Lactobacillus rhamnosus) or placebo group, with matching of gender and chronological age. Both groups received nutritional guidance, and were followed for six months. In all patients the anthropometric assessment was carried out by a nutritionist and data on weight, height and waist circumference (WC) were collected. Body composition was assessed using dual emission X-ray absorptiometry (DXA). RESULTS: After six months, both groups had increased weight, height but reduced body index mass (BMI) standard deviation score, with no differences between groups. After the intervention, both groups showed a reduction in the percentage of total body fat and an increase in lean mass, but only the placebo group showed a reduction in the percentage of trunk fat. However, the variation in these parameters did not differ between groups. CONCLUSIONS: The probiotic group does not seem to have benefited from supplementation. However, we suggest that this reduction in BMI SDS in both groups may have occurred due to improvements in diet because of the nutritional advice given throughout the therapy. We concluded that supplementation with this strain of probiotic was not effective in promoting weight loss or improving the body composition of this population. Sociedade Brasileira de Endocrinologia e Metabologia 2022-10-11 /pmc/articles/PMC10118763/ /pubmed/36219201 http://dx.doi.org/10.20945/2359-3997000000526 Text en https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Marcelo, Thaís Léo Pacheco Pellicciari, Caroline Rosa Artioli, Thiago Olivetti Leiderman, Dânae Braga Diamante Gradinar, Ana Lúcia Torloni Mimica, Marcelo Kochi, Cristiane Probiotic therapy outcomes in body composition of children and adolescent with obesity, a nonrandomized controlled trial |
title | Probiotic therapy outcomes in body composition of children and adolescent with obesity, a nonrandomized controlled trial |
title_full | Probiotic therapy outcomes in body composition of children and adolescent with obesity, a nonrandomized controlled trial |
title_fullStr | Probiotic therapy outcomes in body composition of children and adolescent with obesity, a nonrandomized controlled trial |
title_full_unstemmed | Probiotic therapy outcomes in body composition of children and adolescent with obesity, a nonrandomized controlled trial |
title_short | Probiotic therapy outcomes in body composition of children and adolescent with obesity, a nonrandomized controlled trial |
title_sort | probiotic therapy outcomes in body composition of children and adolescent with obesity, a nonrandomized controlled trial |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118763/ https://www.ncbi.nlm.nih.gov/pubmed/36219201 http://dx.doi.org/10.20945/2359-3997000000526 |
work_keys_str_mv | AT marcelothaisleopacheco probiotictherapyoutcomesinbodycompositionofchildrenandadolescentwithobesityanonrandomizedcontrolledtrial AT pellicciaricarolinerosa probiotictherapyoutcomesinbodycompositionofchildrenandadolescentwithobesityanonrandomizedcontrolledtrial AT artiolithiagoolivetti probiotictherapyoutcomesinbodycompositionofchildrenandadolescentwithobesityanonrandomizedcontrolledtrial AT leidermandanaebragadiamante probiotictherapyoutcomesinbodycompositionofchildrenandadolescentwithobesityanonrandomizedcontrolledtrial AT gradinaranaluciatorloni probiotictherapyoutcomesinbodycompositionofchildrenandadolescentwithobesityanonrandomizedcontrolledtrial AT mimicamarcelo probiotictherapyoutcomesinbodycompositionofchildrenandadolescentwithobesityanonrandomizedcontrolledtrial AT kochicristiane probiotictherapyoutcomesinbodycompositionofchildrenandadolescentwithobesityanonrandomizedcontrolledtrial |